Leucorredução de hemocomponentes na medicina veterinária

Marcia Notomi, Rafael Ruiz De Gopegui Fernandez, Pierre Escodro

Research output: Contribution to journalArticleResearchpeer-review

Abstract

The article aims to inform and update on the use of leukocyte reduction in transfusion therapy, with emphasis on filtering technique of leukocytes and their applicability in veterinary medicine. Leukoreduction is a
procedure to reduce the number of leukocytes from a blood component, in order to avoid the adverse reactions caused by the exposure of leukocytes donor to recipient. Among the various methods of leukoreduction, filtration
has proven to be the most efficient, with retention of approximately 99.9% of leukocytes. In medicine, leukocyte filtration was effective in reducing cases of febrile nonhemolytic reactions, alloimmunization, platelet
refractoriness and cytomegalovirus transmission. Animal studies also observed the reduction of platelet refractoriness cases in dogs and
decreased concentration of proinflammatories mediators of leukoreduction stored bags. The blood components leukocyte reduction is still little known and rarely adopted in the pet therapy. Several benefits have been reported
for the clinical application of LR and potentially another studies could be
conducted with whole blood and its products in veterinary medicine.
Translated title of the contributionLeukoreduction of blood components in veterinary medicine
Original languagePortuguese
Article number2
Pages (from-to)16-32
Number of pages17
JournalVeterinária Noticias
Volume23
Issue number2
DOIs
Publication statusPublished - 2017

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