Lateral Flow Biosensors Based on Gold Nanoparticles

Lourdes Rivas, Alfredo de la Escosura-Muñiz, Josefina Pons, Arben Merkoçi

Research output: Chapter in BookChapterResearchpeer-review

5 Citations (Scopus)


© 2014 Elsevier B.V. The aim of these authors is to offer to the reader the general basis of lateral flow technology and overall of that based on the use of gold nanoparticles, its design, and various useful analytical applications. The historical progress of this technology discussed first is followed by a detailed description of the basic principles, formats, and components including its advantages and limitation. The use of gold nanoparticles as unique labels and their application for detection of different analytes such as proteins, DNA, mycotoxins, pesticides, and heavy metal detection is thoroughly detailed. Finally, new trends on lateral flow technology involving the use of new strategies and materials for improving its sensitivity are also presented and discussed.
Original languageEnglish
Title of host publicationComprehensive Analytical Chemistry
Number of pages36
Publication statusPublished - 1 Jan 2014


  • Gold nanoparticles
  • Immunochromatographic assay
  • Lateral flow assay
  • Paper-based biosensors

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