Laser blastocyst biopsy for preimplantation diagnosis in the human

A. Veiga, M. Sandalinas, M. Benkhalifa, M. Boada, M. Carrera, J. Santaló, P. N. Barri, Y. Ménézo

    Research output: Contribution to journalArticleResearchpeer-review

    97 Citations (Scopus)


    A new methodology for blastocyst biopsy that uses a 1.48 μm diode laser is described. Trophectoderm cells are biopsied after laster zona drilling and culture, fixed and processed for fluorescent in situ hybridisation (FISH) analysis. Preliminary results on the efficiency of the procedure and blastocyst recovery rate are promising. Blastocyst laser biopsy is a useful tool in preimplantation genetic diagnosis (PGD) as it allows a more reliable diagnosis and widens the diagnostic possibilities on account of the higher number of cells obtained in the biopsy.
    Original languageEnglish
    Pages (from-to)351-354
    Issue number4
    Publication statusPublished - 1 Jan 1997


    • Blastocyst
    • Non-contact laser
    • Preimplantation genetic diagnosis
    • Trophectoderm biopsy

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