Laser blastocyst biopsy for preimplantation diagnosis in the human

A. Veiga, M. Sandalinas, M. Benkhalifa, M. Boada, M. Carrera, J. Santaló, P. N. Barri, Y. Ménézo

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    Abstract

    A new methodology for blastocyst biopsy that uses a 1.48 μm diode laser is described. Trophectoderm cells are biopsied after laster zona drilling and culture, fixed and processed for fluorescent in situ hybridisation (FISH) analysis. Preliminary results on the efficiency of the procedure and blastocyst recovery rate are promising. Blastocyst laser biopsy is a useful tool in preimplantation genetic diagnosis (PGD) as it allows a more reliable diagnosis and widens the diagnostic possibilities on account of the higher number of cells obtained in the biopsy.
    Original languageEnglish
    Pages (from-to)351-354
    JournalZygote
    Volume5
    Issue number4
    DOIs
    Publication statusPublished - 1 Jan 1997

    Keywords

    • Blastocyst
    • Non-contact laser
    • Preimplantation genetic diagnosis
    • Trophectoderm biopsy

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  • Cite this

    Veiga, A., Sandalinas, M., Benkhalifa, M., Boada, M., Carrera, M., Santaló, J., Barri, P. N., & Ménézo, Y. (1997). Laser blastocyst biopsy for preimplantation diagnosis in the human. Zygote, 5(4), 351-354. https://doi.org/10.1017/S0967199400003920