Laparoscopic versus open hemihepatectomy: comprehensive comparison of complications and costs at 90 days using a propensity method.

F. Riquelme, C. Muñoz, F. Ausania, A.J. Hessheimer, F. Torres, D. Calatayud, R. Sandomenico, R. García Pérez, J. Ferrer, J. Fuster, J.C. García-Valdecasas, C. Fondevila

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6 Citations (Scopus)


Laparoscopic hemihepatectomy (LHH) may offer advantages over open hemihepatectomy (OHH) in blood loss, recovery, and hospital stay. The aim of this study is to evaluate our recent experience performing hemihepatectomy and compare complications and costs up to 90 days following laparoscopic versus open procedures. Retrospective evaluation of patients undergoing hemihepatectomy at our center 01/2010-12/2018 was performed. Patient, tumor, and surgical characteristics; 90-day complications; and costs were analyzed. Inverse probability of treatment weighting (IPTW) was used to balance covariates. A total of 141 hemihepatectomies were included: 96 OHH and 45 LHH. While operative times were longer for LHH, blood loss and transfusions were less. At 90 days, there were similar rates of liver-specific and surgical complications but fewer medical complications following LHH. Medical complications that arose with greater frequency following OHH were primarily pulmonary complications and urinary and central venous catheter infections. Complications at 90 days were lower following LHH (Clavien-Dindo grade ≥ III OHH 23%, LHH 11%, p = 0.130; Comprehensive Complication Index OHH 20.0 ± 16.1, LHH 10.9 ± 14.2, p = 0.001). While operating costs were higher, costs for hospital stay and readmissions were lower with LHH. Patients undergoing LHH experience a significant reduction in postoperative medical complications and costs, resulting in 90-day cost equity compared with OHH.
Original languageEnglish
Pages (from-to)1041-1051
Number of pages11
JournalUpdates in Surgery
Issue number4
Publication statusPublished - Dec 2020


  • Aged
  • Blood Loss, Surgical
  • Comprehensive complication index
  • Costs and Cost Analysis
  • Female
  • Hemihepatectomy
  • Hepatectomy
  • Humans
  • Laparoscopy
  • Length of Stay
  • Liver Neoplasms
  • Major liver resection
  • Male
  • Middle Aged
  • Operative Time
  • Postoperative Complications
  • Propensity Score
  • Respiratory Tract Diseases
  • Retrospective Studies
  • Time Factors
  • aged
  • comparative study
  • cost
  • economics
  • female
  • human
  • laparoscopy
  • length of stay
  • liver resection
  • liver tumor
  • male
  • middle aged
  • operation duration
  • operative blood loss
  • postoperative complication
  • procedures
  • propensity score
  • respiratory tract disease
  • retrospective study
  • time factor


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