Abstract
Original language | English |
---|---|
Pages (from-to) | 1041-1051 |
Number of pages | 11 |
Journal | Updates in Surgery |
Volume | 72 |
Issue number | 4 |
DOIs | |
Publication status | Published - Dec 2020 |
Keywords
- Aged
- Blood Loss, Surgical
- Comprehensive complication index
- Costs and Cost Analysis
- Female
- Hemihepatectomy
- Hepatectomy
- Humans
- Laparoscopy
- Length of Stay
- Liver Neoplasms
- Major liver resection
- Male
- Middle Aged
- Operative Time
- Postoperative Complications
- Propensity Score
- Respiratory Tract Diseases
- Retrospective Studies
- Time Factors
- aged
- comparative study
- cost
- economics
- female
- human
- laparoscopy
- length of stay
- liver resection
- liver tumor
- male
- middle aged
- operation duration
- operative blood loss
- postoperative complication
- procedures
- propensity score
- respiratory tract disease
- retrospective study
- time factor
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In: Updates in Surgery, Vol. 72, No. 4, 12.2020, p. 1041-1051.
Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Laparoscopic versus open hemihepatectomy: comprehensive comparison of complications and costs at 90 days using a propensity method.
AU - Riquelme, F.
AU - Muñoz, C.
AU - Ausania, F.
AU - Hessheimer, A.J.
AU - Torres, F.
AU - Calatayud, D.
AU - Sandomenico, R.
AU - García Pérez, R.
AU - Ferrer, J.
AU - Fuster, J.
AU - García-Valdecasas, J.C.
AU - Fondevila, C.
N1 - Cited By :4 Export Date: 17 February 2022 Correspondence Address: Fondevila, C.; Department of General and Digestive Surgery, C/ Villarroel 170, Spain; email: cfondevila@ub.edu References: Bhojani, F.D., Fox, A., Pitzul, K., Gallinger, S., Wei, A., Moulton, C.A., Clinical and economic comparison of laparoscopic to open liver resections using a 2-to-1 matched pair analysis: an institutional experience (2012) J Am Coll Surg, 214 (2), pp. 184-195. , PID: 22192894; Ciria, R., Cherqui, D., Geller, D.A., Briceno, J., Wakabayashi, G., Comparative short-term benefits of laparoscopic liver resection: 9000 cases and climbing (2016) Ann Surg, 263 (4), pp. 761-777. , PID: 26700223; Fretland, A.A., Dagenborg, V.J., Bjornelv, G.M.W., Kazaryan, A.M., Kristiansen, R., Fagerland, M.W., Laparoscopic versus open resection for colorectal liver metastases: the OSLO-COMET randomized controlled trial (2018) Ann Surg, 267 (2), pp. 199-207. , PID: 28657937; Macacari, R.L., Coelho, F.F., Bernardo, W.M., Kruger, J.A.P., Jeismann, V.B., Fonseca, G.M., Laparoscopic vs. open left lateral sectionectomy: an update meta-analysis of randomized and non-randomized controlled trials (2019) Int J Surg, 61, pp. 1-10. , PID: 30496866; Abu, H.M., Aldrighetti, L., Dagher, I., Edwin, B., Troisi, R.I., Alikhanov, R., The southampton consensus guidelines for laparoscopic liver surgery: from indication to implementation (2018) Ann Surg, 268 (1), pp. 11-18; van der Poel, M.J., Besselink, M.G., Cipriani, F., Armstrong, T., Takhar, A.S., Van, D.S., Outcome and learning curve in 159 consecutive patients undergoing total laparoscopic hemihepatectomy (2016) JAMA Surg, 151 (10), pp. 923-928. , PID: 27383568; Abu, H.M., Di, F.F., Syed, S., Wiltshire, R., Dimovska, E., Turner, D., Assessment of the financial implications for laparoscopic liver surgery: a single-centre UK cost analysis for minor and major hepatectomy (2013) Surg Endosc, 27 (7), pp. 2542-2550; Medbery, R.L., Chadid, T.S., Sweeney, J.F., Knechtle, S.J., Kooby, D.A., Maithel, S.K., Laparoscopic vs open right hepatectomy: a value-based analysis (2014) J Am Coll Surg, 218 (5), pp. 929-939. , PID: 24680574; Cipriani, F., Ratti, F., Cardella, A., Catena, M., Paganelli, M., Aldrighetti, L., Laparoscopic versus open major hepatectomy: analysis of clinical outcomes and cost effectiveness in a high-volume center (2019) J Gastrointest Surg, 23 (11), pp. 2163-2173. , PID: 30719675; Wabitsch, S., Kastner, A., Haber, P.K., Feldbrugge, L., Winklmann, T., Werner, S., Laparoscopic versus open hemihepatectomy—a cost analysis after propensity score matching (2019) Langenbecks Arch Surg, 404 (4), pp. 469-475. , COI: 1:STN:280:DC%2BB3M7jsVyntQ%3D%3D, PID: 31065781; Rossler, F., Sapisochin, G., Song, G., Lin, Y.H., Simpson, M.A., Hasegawa, K., Defining benchmarks for major liver surgery: a multicenter analysis of 5202 living liver donors (2016) Ann Surg, 264 (3), pp. 492-500. , PID: 27433909; Majno, P.E., Mentha, G., Morel, P., Segalin, A., Azoulay, D., Oberholzer, J., Arantius’ ligament approach to the left hepatic vein and to the common trunk (2002) J Am Coll Surg, 195 (5), pp. 737-739. , PID: 12437267; Charlson, M., Szatrowski, T.P., Peterson, J., Gold, J., Validation of a combined comorbidity index (1994) J Clin Epidemiol, 47 (11), pp. 1245-1251. , COI: 1:STN:280:DyaK2M3jvFantQ%3D%3D; Dindo, D., Demartines, N., Clavien, P.A., Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey (2004) Ann Surg, 240 (2), pp. 205-213. , PID: 15273542; Slankamenac, K., Graf, R., Barkun, J., Puhan, M.A., Clavien, P.A., The comprehensive complication index: a novel continuous scale to measure surgical morbidity (2013) Ann Surg, 258 (1), pp. 1-7. , PID: 23728278; Koch, M., Garden, O.J., Padbury, R., Rahbari, N.N., Adam, R., Capussotti, L., Bile leakage after hepatobiliary and pancreatic surgery: a definition and grading of severity by the International Study Group of Liver Surgery (2011) Surgery, 149 (5), pp. 680-688. , PID: 21316725; Rahbari, N.N., Garden, O.J., Padbury, R., Brooke-Smith, M., Crawford, M., Adam, R., Posthepatectomy liver failure: a definition and grading by the International Study Group of Liver Surgery (ISGLS) (2011) Surgery, 149 (5), pp. 713-724. , PID: 21236455; Ishizawa, T., Hasegawa, K., Kokudo, N., Sano, K., Imamura, H., Beck, Y., Risk factors and management of ascites after liver resection to treat hepatocellular carcinoma (2009) Arch Surg, 144 (1), pp. 46-51. , PID: 19153324; (2016), https://www.ine.es/jaxiT3/Tabla.htm?, Índices de Precios de Consumo. Base. Available from; Pezzi, C.M., Mallin, K., Mendez, A.S., Greer, G.E., Putnam, J.B., Jr., Ninety-day mortality after resection for lung cancer is nearly double 30-day mortality (2014) J Thorac Cardiovasc Surg, 148 (5), pp. 2269-2277. , PID: 25172318; Swanson, R.S., Pezzi, C.M., Mallin, K., Loomis, A.M., Winchester, D.P., The 90-day mortality after pancreatectomy for cancer is double the 30-day mortality: more than 20,000 resections from the national cancer data base (2014) Ann Surg Oncol, 21 (13), pp. 4059-4067. , PID: 25190121; Talsma, A.K., Lingsma, H.F., Steyerberg, E.W., Wijnhoven, B.P., Van Lanschot, J.J., The 30-day versus in-hospital and 90-day mortality after esophagectomy as indicators for quality of care (2014) Ann Surg, 260 (2), pp. 267-273. , PID: 25350650; Mise, Y., Vauthey, J.N., Zimmitti, G., Parker, N.H., Conrad, C., Aloia, T.A., Ninety-day postoperative mortality is a legitimate measure of hepatopancreatobiliary surgical quality (2015) Ann Surg, 262 (6), pp. 1071-1078. , PID: 25590497; Schiergens, T.S., Dorsch, M., Mittermeier, L., Brand, K., Kuchenhoff, H., Lee, S.M., Thirty-day mortality leads to underestimation of postoperative death after liver resection: a novel method to define the acute postoperative period (2015) Surgery, 158 (6), pp. 1530-1537. , PID: 26298028; Vonlanthen, R., Slankamenac, K., Breitenstein, S., Puhan, M.A., Muller, M.K., Hahnloser, D., The impact of complications on costs of major surgical procedures: a cost analysis of 1200 patients (2011) Ann Surg, 254 (6), pp. 907-913. , PID: 21562405; Staiger, R.D., Cimino, M., Javed, A., Biondo, S., Fondevila, C., Perinel, J., The Comprehensive Complication Index (CCI(R)) is a novel cost assessment tool for surgical procedures (2018) Ann Surg, 268 (5), pp. 784-791. , PID: 30272585; Cipriani, F., Alzoubi, M., Fuks, D., Ratti, F., Kawai, T., Berardi, G., Pure laparoscopic versus open hemihepatectomy: a critical assessment and realistic expectations—a propensity score-based analysis of right and left hemihepatectomies from nine European tertiary referral centers (2020) J Hepatobiliary Pancreat Sci, 27 (1), pp. 3-15. , PID: 31419040; Hessheimer, A.J., de la Martinez, M.L., Adel Al, S.F., Espinoza, A.S., Ausania, F., Fondevila, C., Somatostatin and the “small-for-size” liver (2019) Int J Mol Sci, 20 (10), p. 2512. , COI: 1:CAS:528:DC%2BB3cXosVKlsA%3D%3D; Wong-Lun-Hing, E.M., van Dam, R.M., van Breukelen, G.J., Tanis, P.J., Ratti, F., Van, H.R., Randomized clinical trial of open versus laparoscopic left lateral hepatic sectionectomy within an enhanced recovery after surgery programme (ORANGE II study) (2017) Br J Surg, 104 (5), pp. 525-535. , COI: 1:STN:280:DC%2BC1c3gvVyktQ%3D%3D, PID: 28138958; https://clinicaltrials.gov/ct2/show/NCT01441856, ClinicalTrials.gov. Bethesda (MD): National Library of Medicine (US). 2011 Sep 28. Identifier NCT01441856, The ORANGE II PLUS - Trial: Open Versus Laparoscopic Hemihepatectomy. Available from; (2017) Identifier NCT03270917, ORANGE SEGMENTS: Open versus Laparoscopic Parenchymal Preserving Postero-Superior Liver Segment Resection, , https://clinicaltrials.gov/ct2/show/NCT03270917, Sep 1, Available from; Yang, T., Zhang, J., Lu, J.H., Yang, G.S., Wu, M.C., Yu, W.F., Risk factors influencing postoperative outcomes of major hepatic resection of hepatocellular carcinoma for patients with underlying liver diseases (2011) World J Surg, 35 (9), pp. 2073-2082. , PID: 21656309; Nobili, C., Marzano, E., Oussoultzoglou, E., Rosso, E., Addeo, P., Bachellier, P., Multivariate analysis of risk factors for pulmonary complications after hepatic resection (2012) Ann Surg, 255 (3), pp. 540-550. , PID: 22330041; Fuks, D., Cauchy, F., Fteriche, S., Nomi, T., Schwarz, L., Dokmak, S., Laparoscopy decreases pulmonary complications in patients undergoing major liver resection: a propensity score analysis (2016) Ann Surg, 263 (2), pp. 353-361. , PID: 25607769; Torres, F., Rios, J., Saez-Penataro, J., Pontes, C., Is propensity score analysis a valid surrogate of randomization for the avoidance of allocation bias? (2017) Semin Liver Dis, 37 (3), pp. 275-286. , PID: 28847037; Moris, D., Dimitroulis, D., Vernadakis, S., Papalampros, A., Spartalis, E., Petrou, A., Parenchymal-sparing hepatectomy as the new doctrine in the treatment of liver-metastatic colorectal disease: beyond oncological outcomes (2017) Anticancer Res, 37 (1), pp. 9-14. , PID: 28011468; Halls, M.C., Cipriani, F., Berardi, G., Barkhatov, L., Lainas, P., Alzoubi, M., Conversion for unfavorable intraoperative events results in significantly worse outcomes during laparoscopic liver resection: lessons learned from a multicenter review of 2861 cases (2018) Ann Surg, 268 (6), pp. 1051-1057. , PID: 28582270
PY - 2020/12
Y1 - 2020/12
N2 - Laparoscopic hemihepatectomy (LHH) may offer advantages over open hemihepatectomy (OHH) in blood loss, recovery, and hospital stay. The aim of this study is to evaluate our recent experience performing hemihepatectomy and compare complications and costs up to 90 days following laparoscopic versus open procedures. Retrospective evaluation of patients undergoing hemihepatectomy at our center 01/2010-12/2018 was performed. Patient, tumor, and surgical characteristics; 90-day complications; and costs were analyzed. Inverse probability of treatment weighting (IPTW) was used to balance covariates. A total of 141 hemihepatectomies were included: 96 OHH and 45 LHH. While operative times were longer for LHH, blood loss and transfusions were less. At 90 days, there were similar rates of liver-specific and surgical complications but fewer medical complications following LHH. Medical complications that arose with greater frequency following OHH were primarily pulmonary complications and urinary and central venous catheter infections. Complications at 90 days were lower following LHH (Clavien-Dindo grade ≥ III OHH 23%, LHH 11%, p = 0.130; Comprehensive Complication Index OHH 20.0 ± 16.1, LHH 10.9 ± 14.2, p = 0.001). While operating costs were higher, costs for hospital stay and readmissions were lower with LHH. Patients undergoing LHH experience a significant reduction in postoperative medical complications and costs, resulting in 90-day cost equity compared with OHH.
AB - Laparoscopic hemihepatectomy (LHH) may offer advantages over open hemihepatectomy (OHH) in blood loss, recovery, and hospital stay. The aim of this study is to evaluate our recent experience performing hemihepatectomy and compare complications and costs up to 90 days following laparoscopic versus open procedures. Retrospective evaluation of patients undergoing hemihepatectomy at our center 01/2010-12/2018 was performed. Patient, tumor, and surgical characteristics; 90-day complications; and costs were analyzed. Inverse probability of treatment weighting (IPTW) was used to balance covariates. A total of 141 hemihepatectomies were included: 96 OHH and 45 LHH. While operative times were longer for LHH, blood loss and transfusions were less. At 90 days, there were similar rates of liver-specific and surgical complications but fewer medical complications following LHH. Medical complications that arose with greater frequency following OHH were primarily pulmonary complications and urinary and central venous catheter infections. Complications at 90 days were lower following LHH (Clavien-Dindo grade ≥ III OHH 23%, LHH 11%, p = 0.130; Comprehensive Complication Index OHH 20.0 ± 16.1, LHH 10.9 ± 14.2, p = 0.001). While operating costs were higher, costs for hospital stay and readmissions were lower with LHH. Patients undergoing LHH experience a significant reduction in postoperative medical complications and costs, resulting in 90-day cost equity compared with OHH.
KW - Aged
KW - Blood Loss, Surgical
KW - Comprehensive complication index
KW - Costs and Cost Analysis
KW - Female
KW - Hemihepatectomy
KW - Hepatectomy
KW - Humans
KW - Laparoscopy
KW - Length of Stay
KW - Liver Neoplasms
KW - Major liver resection
KW - Male
KW - Middle Aged
KW - Operative Time
KW - Postoperative Complications
KW - Propensity Score
KW - Respiratory Tract Diseases
KW - Retrospective Studies
KW - Time Factors
KW - aged
KW - comparative study
KW - cost
KW - economics
KW - female
KW - human
KW - laparoscopy
KW - length of stay
KW - liver resection
KW - liver tumor
KW - male
KW - middle aged
KW - operation duration
KW - operative blood loss
KW - postoperative complication
KW - procedures
KW - propensity score
KW - respiratory tract disease
KW - retrospective study
KW - time factor
UR - https://doi.org/10.1007/s13304-020-00854-y
UR - http://www.scopus.com/inward/record.url?scp=85088842561&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/1a479934-b30e-3545-bb6b-66812c6b9056/
U2 - https://doi.org/10.1007/s13304-020-00854-y
DO - https://doi.org/10.1007/s13304-020-00854-y
M3 - Article
C2 - 32734578
SN - 2038-131X
VL - 72
SP - 1041
EP - 1051
JO - Updates in Surgery
JF - Updates in Surgery
IS - 4
ER -