Lack of association between the LPR and VNTR polymorphisms of the serotonin transporter gene and cocaine dependence in a Spanish sample

Alba Tristán-Noguero, Noèlia Fernàndez-Castillo, Carlos Roncero, Cristina Sánchez-Mora, Josep Antoni Ramos-Quiroga, Constanza Daigre, Ángel Egido, Joan Alvarós, Gemma Prat, Miquel Casas, Bru Cormand, Marta Ribasés

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Abstract

We genotyped the LPR and VNTR polymorphisms of the serotonin transporter gene in 504 cocaine-dependent patients and 508 controls. No association was detected with either polymorphism or with any haplotype combination. This study provided no evidence that these polymorphisms confer susceptibility to cocaine dependence in our sample. © 2013 Elsevier Ireland Ltd.
Original languageEnglish
Pages (from-to)1287-1289
JournalPsychiatry Research
Volume210
Issue number3
DOIs
Publication statusPublished - 30 Dec 2013

Keywords

  • 5HTT
  • Association study
  • Drug addiction

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    Tristán-Noguero, A., Fernàndez-Castillo, N., Roncero, C., Sánchez-Mora, C., Ramos-Quiroga, J. A., Daigre, C., Egido, Á., Alvarós, J., Prat, G., Casas, M., Cormand, B., & Ribasés, M. (2013). Lack of association between the LPR and VNTR polymorphisms of the serotonin transporter gene and cocaine dependence in a Spanish sample. Psychiatry Research, 210(3), 1287-1289. https://doi.org/10.1016/j.psychres.2013.09.004