KIT-positive gastrointestinal stromal tumours in two Spanish ibex (Capra pyrenaica hispanica)

Roser Velarde, Gregorio Mentaberre, Joaquín Sánchez, Ignasi Marco, Santiago Lavín

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5 Citations (Scopus)

Abstract

Gastrointestinal mesenchymal tumours from two Spanish ibex (Capra pyrenaica hispanica) were examined grossly, histologically and immunohistochemically. One neoplasm was a 1.5 kg tan multinodular cavitated mass in the forestomach. The other tumour was a firm mural mass 1.2 cm in diameter in the colon. Microscopically, both tumours were formed mainly by spindle shaped cells arranged in closely packed interlacing fascicles. Neoplastic cells in both tumours labelled positively for KIT (CD117), vimentin and α-smooth muscle actin. These findings suggest that both neoplasms were gastrointestinal stromal tumours and most likely to be derived from the interstitial cells of Cajal or their progenitor cells. © 2007 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)445-447
JournalVeterinary Journal
Volume177
DOIs
Publication statusPublished - 1 Sep 2008

Keywords

  • Capra pyrenaica hispanica
  • Gastrointestinal stromal tumours
  • Immunohistochemistry
  • Interstitial cells of cajal
  • KIT
  • Spanish ibex

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