KIT-positive gastrointestinal stromal tumours in two Spanish ibex (Capra pyrenaica hispanica)

Roser Velarde; Gregorio Mentaberre; Joaquín Sánchez; Ignasi Marco; Santiago Lavín

doi:https://doi.org/10.1016/j.tvjl.2007.06.013

KIT-positive gastrointestinal stromal tumours in two Spanish ibex (Capra pyrenaica hispanica)

Roser Velarde, Gregorio Mentaberre, Joaquín Sánchez, Ignasi Marco, Santiago Lavín

Department of Animal Medicine and Surgery

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Abstract

Gastrointestinal mesenchymal tumours from two Spanish ibex (Capra pyrenaica hispanica) were examined grossly, histologically and immunohistochemically. One neoplasm was a 1.5 kg tan multinodular cavitated mass in the forestomach. The other tumour was a firm mural mass 1.2 cm in diameter in the colon. Microscopically, both tumours were formed mainly by spindle shaped cells arranged in closely packed interlacing fascicles. Neoplastic cells in both tumours labelled positively for KIT (CD117), vimentin and α-smooth muscle actin. These findings suggest that both neoplasms were gastrointestinal stromal tumours and most likely to be derived from the interstitial cells of Cajal or their progenitor cells. © 2007 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	445-447
Journal	Veterinary Journal
Volume	177
DOIs	https://doi.org/10.1016/j.tvjl.2007.06.013
Publication status	Published - 1 Sept 2008

Keywords

Capra pyrenaica hispanica
Gastrointestinal stromal tumours
Immunohistochemistry
Interstitial cells of cajal
KIT
Spanish ibex

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@article{51c24476a047422b90a15959bc222ea6,

title = "KIT-positive gastrointestinal stromal tumours in two Spanish ibex (Capra pyrenaica hispanica)",

abstract = "Gastrointestinal mesenchymal tumours from two Spanish ibex (Capra pyrenaica hispanica) were examined grossly, histologically and immunohistochemically. One neoplasm was a 1.5 kg tan multinodular cavitated mass in the forestomach. The other tumour was a firm mural mass 1.2 cm in diameter in the colon. Microscopically, both tumours were formed mainly by spindle shaped cells arranged in closely packed interlacing fascicles. Neoplastic cells in both tumours labelled positively for KIT (CD117), vimentin and α-smooth muscle actin. These findings suggest that both neoplasms were gastrointestinal stromal tumours and most likely to be derived from the interstitial cells of Cajal or their progenitor cells. {\textcopyright} 2007 Elsevier Ltd. All rights reserved.",

keywords = "Capra pyrenaica hispanica, Gastrointestinal stromal tumours, Immunohistochemistry, Interstitial cells of cajal, KIT, Spanish ibex",

author = "Roser Velarde and Gregorio Mentaberre and Joaqu{\'i}n S{\'a}nchez and Ignasi Marco and Santiago Lav{\'i}n",

year = "2008",

month = sep,

day = "1",

doi = "https://doi.org/10.1016/j.tvjl.2007.06.013",

language = "English",

volume = "177",

pages = "445--447",

}

TY - JOUR

T1 - KIT-positive gastrointestinal stromal tumours in two Spanish ibex (Capra pyrenaica hispanica)

AU - Velarde, Roser

AU - Mentaberre, Gregorio

AU - Sánchez, Joaquín

AU - Marco, Ignasi

AU - Lavín, Santiago

PY - 2008/9/1

Y1 - 2008/9/1

N2 - Gastrointestinal mesenchymal tumours from two Spanish ibex (Capra pyrenaica hispanica) were examined grossly, histologically and immunohistochemically. One neoplasm was a 1.5 kg tan multinodular cavitated mass in the forestomach. The other tumour was a firm mural mass 1.2 cm in diameter in the colon. Microscopically, both tumours were formed mainly by spindle shaped cells arranged in closely packed interlacing fascicles. Neoplastic cells in both tumours labelled positively for KIT (CD117), vimentin and α-smooth muscle actin. These findings suggest that both neoplasms were gastrointestinal stromal tumours and most likely to be derived from the interstitial cells of Cajal or their progenitor cells. © 2007 Elsevier Ltd. All rights reserved.

AB - Gastrointestinal mesenchymal tumours from two Spanish ibex (Capra pyrenaica hispanica) were examined grossly, histologically and immunohistochemically. One neoplasm was a 1.5 kg tan multinodular cavitated mass in the forestomach. The other tumour was a firm mural mass 1.2 cm in diameter in the colon. Microscopically, both tumours were formed mainly by spindle shaped cells arranged in closely packed interlacing fascicles. Neoplastic cells in both tumours labelled positively for KIT (CD117), vimentin and α-smooth muscle actin. These findings suggest that both neoplasms were gastrointestinal stromal tumours and most likely to be derived from the interstitial cells of Cajal or their progenitor cells. © 2007 Elsevier Ltd. All rights reserved.

KW - Capra pyrenaica hispanica

KW - Gastrointestinal stromal tumours

KW - Immunohistochemistry

KW - Interstitial cells of cajal

KW - KIT

KW - Spanish ibex

U2 - https://doi.org/10.1016/j.tvjl.2007.06.013

DO - https://doi.org/10.1016/j.tvjl.2007.06.013

M3 - Article

VL - 177

SP - 445

EP - 447

ER -

KIT-positive gastrointestinal stromal tumours in two Spanish ibex (Capra pyrenaica hispanica)

Abstract

Keywords

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