Isolation and characterization of serologically reactive lipooligosaccharides from Mycobacterium tuberculosis

F. Papa, P. Cruaud, M. Luquin, M. F. Thorel, K. S. Goh, H. L. David

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Abstract

Two major highly polar antigenic glycolipids were isolated from recent isolates of Mycobacterium tuberculosis from a wide range of geographical origins. The occurrence of these polar glycolipids was demonstrated by isolation, purification and chromatographic characterization and/or serological procedures in 12 strains. Based on their chromatographic properties, these polar glycolipids belong to the lipooligosaccharide family. Preliminary data on the use of these newly described antigens in the serodiagnosis of tubercolosis is presented. © 1993.
Original languageEnglish
Pages (from-to)91-99
JournalResearch in Microbiology
Volume144
Issue number2
DOIs
Publication statusPublished - 1 Jan 1993

Keywords

  • Characterization, Antigenicity, Diagnosis
  • Glycolipid, Mycobacterium tuberculosis, LOS, Tuberculosis

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