Is joint hypermobility related to anxiety in a nonclinical population also?

Antonio Bulbena, Albert Agulló, Guillem Pailhez, Rocio Martín-Santos, Miquel Porta, Joan Guitart, Jordi Gago

Research output: Contribution to journalArticleResearchpeer-review

58 Citations (Scopus)


This study examines the association between joint hypermobility syndrome and anxiety in a non-clinical sample. Subjects (N = 526) receiving a medical check-up were assessed with the Hospital del Mar hypermobility criteria and the State-Trait Anxiety Inventory. Scores for trait anxiety, and to a lesser extent state anxiety, were significantly higher among subjects with joint hypermobility syndrome than among subjects without this syndrome (median trait anxiety scores for women: 17 versus 11; median scores for men: 13 versus 1). These findings indicate that the association of joint hypermobility syndrome and anxiety holds even for subjects with no psychiatric diagnosis. Therefore, it seems that this benign connective tissue disorder is a predisposing factor for trait anxiety. However, it is necessary to further explore and define the biological basis of this syndrome, as well as its associations and clinical expressions, which interact with great complexity.
Original languageEnglish
Pages (from-to)432-437
Publication statusPublished - 1 Jan 2004


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