Ion mobility spectrometry as a high-throughput analytical tool in occupational pyrethroid exposure

S. Armenta, M. Blanco

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Abstract

The capabilities of ion mobility spectrometry (IMS) as a high throughput and green analytical tool in the occupational health and safety control, using pyrethroids as models has been evidenced. The method used for dermal and inhalation exposure assessment is based on the passive pyrethroid sampling using Teflon membranes, direct thermal extraction of the pyrethroids, and measurement of the vaporized analytes by IMS without reagent and solvent consumption. The IMS signatures of the studied synthetic pyrethroids under atmospheric pressure chemical ionization by investigating the formed negative ion products have been obtained. The main advantages of the proposed procedure are related to the obtained limits of detection, ranging from 0.08 to 5 ng, the simplicity of measurement, the lack of sample treatment, and therefore, solvent consumption and waste generation, and finally, the speed of analysis. © Springer-Verlag 2012.
Original languageEnglish
Pages (from-to)635-648
JournalAnalytical and Bioanalytical Chemistry
Volume404
Issue number3
DOIs
Publication statusPublished - 1 Aug 2012

Keywords

  • Dermal
  • Green analytical chemistry
  • Ion mobility spectrometry
  • Occupational exposure
  • Pyrethroids
  • Respiratory

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