TY - JOUR
T1 - Invasive device-associated infections caused by Pseudomonas aeruginosa in critically ill patients: evolution over 10 years
AU - Álvarez-Lerma, F.
AU - Olaechea-Astigarraga, P.
AU - Palomar-Martínez, M.
AU - Catalan, M.
AU - Nuvials, X.
AU - Gimeno, R.
AU - Gracia-Arnillas, M. P.
AU - Seijas-Betolaza, I.
PY - 2018/11/1
Y1 - 2018/11/1
N2 - © 2018 The Healthcare Infection Society Invasive device-associated infections caused by Pseudomonas aeruginosa over 10 years (2007–2016) were assessed based on data from the ENVIN-HELICS registry (200 Spanish intensive care units). P. aeruginosa was the leading pathogen except in the last two years in which there was a slight decrease, with Escherichia coli as the leading aetiology. The rate of infections caused by P. aeruginosa remained between 12.0% and 14.6% throughout the study period. There was a significant increase of isolates resistant to imipenem, meropenem, ceftazidime, cefepime, and piperacillin–tazobactam. Multidrug-resistant and the sum of extensively drug- and pandrug-resistant strains also increased. Resistance to anti-pseudomonal antimicrobials remains a matter of concern.
AB - © 2018 The Healthcare Infection Society Invasive device-associated infections caused by Pseudomonas aeruginosa over 10 years (2007–2016) were assessed based on data from the ENVIN-HELICS registry (200 Spanish intensive care units). P. aeruginosa was the leading pathogen except in the last two years in which there was a slight decrease, with Escherichia coli as the leading aetiology. The rate of infections caused by P. aeruginosa remained between 12.0% and 14.6% throughout the study period. There was a significant increase of isolates resistant to imipenem, meropenem, ceftazidime, cefepime, and piperacillin–tazobactam. Multidrug-resistant and the sum of extensively drug- and pandrug-resistant strains also increased. Resistance to anti-pseudomonal antimicrobials remains a matter of concern.
KW - Anti-pseudomonal drugs
KW - Antimicrobial resistance
KW - Critically ill
KW - Intensive care unit
KW - Invasive device-associated infection
KW - Pseudomonas aeruginosa
U2 - 10.1016/j.jhin.2018.04.027
DO - 10.1016/j.jhin.2018.04.027
M3 - Article
C2 - 29751023
VL - 100
SP - e204-e208
JO - Journal of Hospital Infection
JF - Journal of Hospital Infection
SN - 0195-6701
ER -