Interstitial radiation therapy with iridium-192 in soft tissue sarcomas. Experience of the 'Hospital de la Santa Cruz y San Pablo', Barcelona

F. Guedea, J. Sole, J. Balart, J. Craven-Bartle, J. Majo, S. Sabater

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Purpose: Experience and results of conservative treatment of the soft tissue sarcomas in the Hospital de la Santa Creu i Sant Pau. Pacients and methods: Eighteen patients with a soft tissue sarcoma were treated between March 1984 and January 1989 by conservative surgical excision and interstitial implant using iridium 192 wires, associated in eleven patients with external radiation therapy. Results: One patient who developed local recurrence 34 months later underwent arm amputation and is alive and well 45 months following initial treatment. Three patients developed lung metastasis 6, 17 and 24 months later and died 12, 22 and 53 months respectively after initial treatment. Overall survival rate was 79% at 7 years and disease-free survival rate was 77 at 7 years. Conclusion: Our presents results in soft tissue sarcomas have led us to advocate the combination of conservative surgery with postoperative external radiation therapy supplemented with brachytherapy boost.
Original languageEnglish
Pages (from-to)39-44
JournalOncologia
Volume18
Issue number11
Publication statusPublished - 1 Dec 1995

Keywords

  • brachytherapy
  • conservative treatment
  • soft tissue sarcoma

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