Integration of a glucose biosensor based on an epoxy-graphite- TTF·TCNQ-GOD biocomposite into a FIA system

X. Llopis; A. Merkoçi; M. Del Valle; S. Alegret

doi:10.1016/j.snb.2004.12.006

Integration of a glucose biosensor based on an epoxy-graphite- TTF·TCNQ-GOD biocomposite into a FIA system

X. Llopis, A. Merkoçi, M. Del Valle, S. Alegret

Department of Chemistry

Research output: Contribution to journal › Article › Research › peer-review

23 Citations (Scopus)

Abstract

An amperometric glucose biosensor based on graphite and non-conducting epoxy resin biocomposite was constructed. Glucose oxidase (GOD) and the tetrathiafulvalene-tetracyanoquinodimethane (TTF·TCNQ) conducting organic salt were incorporated into the bulk of the composite to form a renewable biosensor. Several graphite-TTF·TCNQ ratios (w/w) were studied in order to select the best biosensor to be integrated in a FIA system for the automated detection of glucose. The optimal amount of GOD in the composite was studied as well. The selection was based on the analytical response of the electrodes. Best results were obtained by an electrode whose composition was 5% GOD, 76% polymer, 9.5% graphite and 9.5% TTF·TCNQ. An especially designed flow amperometric cell was constructed so that the biosensor could be integrated into a FIA system and glucose in beverage samples could be determined. © 2004 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	742-748
Journal	Sensors and Actuators, B: Chemical
Volume	107
Issue number	2
DOIs	https://doi.org/10.1016/j.snb.2004.12.006
Publication status	Published - 29 Jun 2005

Keywords

Amperometric detection
Biosensor
FIA
Glucose
Graphite-epoxy biocomposite
TTF·TCNQ

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.snb.2004.12.006

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title = "Integration of a glucose biosensor based on an epoxy-graphite- TTF·TCNQ-GOD biocomposite into a FIA system",

abstract = "An amperometric glucose biosensor based on graphite and non-conducting epoxy resin biocomposite was constructed. Glucose oxidase (GOD) and the tetrathiafulvalene-tetracyanoquinodimethane (TTF·TCNQ) conducting organic salt were incorporated into the bulk of the composite to form a renewable biosensor. Several graphite-TTF·TCNQ ratios (w/w) were studied in order to select the best biosensor to be integrated in a FIA system for the automated detection of glucose. The optimal amount of GOD in the composite was studied as well. The selection was based on the analytical response of the electrodes. Best results were obtained by an electrode whose composition was 5% GOD, 76% polymer, 9.5% graphite and 9.5% TTF·TCNQ. An especially designed flow amperometric cell was constructed so that the biosensor could be integrated into a FIA system and glucose in beverage samples could be determined. {\textcopyright} 2004 Elsevier B.V. All rights reserved.",

keywords = "Amperometric detection, Biosensor, FIA, Glucose, Graphite-epoxy biocomposite, TTF·TCNQ",

author = "X. Llopis and A. Merko{\c c}i and {Del Valle}, M. and S. Alegret",

year = "2005",

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doi = "10.1016/j.snb.2004.12.006",

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journal = "Sensors and Actuators, B: Chemical",

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T1 - Integration of a glucose biosensor based on an epoxy-graphite- TTF·TCNQ-GOD biocomposite into a FIA system

AU - Llopis, X.

AU - Merkoçi, A.

AU - Del Valle, M.

AU - Alegret, S.

PY - 2005/6/29

Y1 - 2005/6/29

N2 - An amperometric glucose biosensor based on graphite and non-conducting epoxy resin biocomposite was constructed. Glucose oxidase (GOD) and the tetrathiafulvalene-tetracyanoquinodimethane (TTF·TCNQ) conducting organic salt were incorporated into the bulk of the composite to form a renewable biosensor. Several graphite-TTF·TCNQ ratios (w/w) were studied in order to select the best biosensor to be integrated in a FIA system for the automated detection of glucose. The optimal amount of GOD in the composite was studied as well. The selection was based on the analytical response of the electrodes. Best results were obtained by an electrode whose composition was 5% GOD, 76% polymer, 9.5% graphite and 9.5% TTF·TCNQ. An especially designed flow amperometric cell was constructed so that the biosensor could be integrated into a FIA system and glucose in beverage samples could be determined. © 2004 Elsevier B.V. All rights reserved.

AB - An amperometric glucose biosensor based on graphite and non-conducting epoxy resin biocomposite was constructed. Glucose oxidase (GOD) and the tetrathiafulvalene-tetracyanoquinodimethane (TTF·TCNQ) conducting organic salt were incorporated into the bulk of the composite to form a renewable biosensor. Several graphite-TTF·TCNQ ratios (w/w) were studied in order to select the best biosensor to be integrated in a FIA system for the automated detection of glucose. The optimal amount of GOD in the composite was studied as well. The selection was based on the analytical response of the electrodes. Best results were obtained by an electrode whose composition was 5% GOD, 76% polymer, 9.5% graphite and 9.5% TTF·TCNQ. An especially designed flow amperometric cell was constructed so that the biosensor could be integrated into a FIA system and glucose in beverage samples could be determined. © 2004 Elsevier B.V. All rights reserved.

KW - Amperometric detection

KW - Biosensor

KW - FIA

KW - Glucose

KW - Graphite-epoxy biocomposite

KW - TTF·TCNQ

U2 - 10.1016/j.snb.2004.12.006

DO - 10.1016/j.snb.2004.12.006

M3 - Article

VL - 107

SP - 742

EP - 748

JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

SN - 0925-4005

IS - 2

ER -

Integration of a glucose biosensor based on an epoxy-graphite- TTF·TCNQ-GOD biocomposite into a FIA system

Abstract

Keywords

UN SDGs

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