Influence of primary diagnosis and complications on visual outcome in patients receiving a boston type 1 keratoprosthesis

Valeria De Rezende Couto Nascimento; Maria Fideliz De La Paz; Jurja Rosandic; Josef Stoiber; Orang Seyeddain; Günther Grabner; Juan Alvarez De Toledo; Rafael I. Barraquer; Ralph Michael

doi:10.1159/000358332

Influence of primary diagnosis and complications on visual outcome in patients receiving a boston type 1 keratoprosthesis

Valeria De Rezende Couto Nascimento, Maria Fideliz De La Paz, Jurja Rosandic, Josef Stoiber, Orang Seyeddain, Günther Grabner, Juan Alvarez De Toledo, Rafael I. Barraquer, Ralph Michael

Research output: Contribution to journal › Article › Research › peer-review

5 Citations (Scopus)

Abstract

Purpose: To analyse how primary diagnosis and complications affect the evolution of post-operative visual acuity (VA). Methods: We performed retrospective chart analysis on 59 eyes in 57 patients with various diagnoses, most of which were non-standard indications for Boston type 1 keratoprosthesis (Kpro) implantation. The follow-up period was at least 3 months. Patients were classified based on the evolution of post-operative VA: group A demonstrated stable VA improvement, group B lost VA improvement and group C no significant VA improvement. Results: We assigned 46% of our cases to group A with stable VA improvement, 32% to group B with lost VA improvement, and 22% to group C with no VA improvement. The number of graft failures before Kpro implantation did not influence VA outcome. Except for the relatively good VA outcome in chemical burn and radiation injury patients, there seems to be no association between primary diagnosis and positive or negative VA outcome. Only 9% of patients with posterior segment complications and 20% with infections and associated pathologies were assigned to group A. Conclusion: Most cases (78%) showed improvement in VA after Boston type 1 Kpro (groups A and B). Posterior segment complications and infections mostly resulted in persistent loss of vision. These complications should be prevented and carefully treated. © 2014 S. Karger AG, Basel.

Original language	English
Pages (from-to)	9-16
Journal	Ophthalmic Research
Volume	52
Issue number	1
DOIs	https://doi.org/10.1159/000358332
Publication status	Published - 1 Jan 2014

Keywords

Keratoprosthesis
Post-operative complications
Primary diagnosis
Visual outcome

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De Rezende Couto Nascimento, V., De La Paz, M. F., Rosandic, J., Stoiber, J., Seyeddain, O., Grabner, G., De Toledo, J. A., Barraquer, R. I., & Michael, R. (2014). Influence of primary diagnosis and complications on visual outcome in patients receiving a boston type 1 keratoprosthesis. Ophthalmic Research, 52(1), 9-16. https://doi.org/10.1159/000358332

De Rezende Couto Nascimento, Valeria ; De La Paz, Maria Fideliz ; Rosandic, Jurja ; Stoiber, Josef ; Seyeddain, Orang ; Grabner, Günther ; De Toledo, Juan Alvarez ; Barraquer, Rafael I. ; Michael, Ralph. / Influence of primary diagnosis and complications on visual outcome in patients receiving a boston type 1 keratoprosthesis. In: Ophthalmic Research. 2014 ; Vol. 52, No. 1. pp. 9-16.

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abstract = "Purpose: To analyse how primary diagnosis and complications affect the evolution of post-operative visual acuity (VA). Methods: We performed retrospective chart analysis on 59 eyes in 57 patients with various diagnoses, most of which were non-standard indications for Boston type 1 keratoprosthesis (Kpro) implantation. The follow-up period was at least 3 months. Patients were classified based on the evolution of post-operative VA: group A demonstrated stable VA improvement, group B lost VA improvement and group C no significant VA improvement. Results: We assigned 46% of our cases to group A with stable VA improvement, 32% to group B with lost VA improvement, and 22% to group C with no VA improvement. The number of graft failures before Kpro implantation did not influence VA outcome. Except for the relatively good VA outcome in chemical burn and radiation injury patients, there seems to be no association between primary diagnosis and positive or negative VA outcome. Only 9% of patients with posterior segment complications and 20% with infections and associated pathologies were assigned to group A. Conclusion: Most cases (78%) showed improvement in VA after Boston type 1 Kpro (groups A and B). Posterior segment complications and infections mostly resulted in persistent loss of vision. These complications should be prevented and carefully treated. {\textcopyright} 2014 S. Karger AG, Basel.",

keywords = "Keratoprosthesis, Post-operative complications, Primary diagnosis, Visual outcome",

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Influence of primary diagnosis and complications on visual outcome in patients receiving a boston type 1 keratoprosthesis. / De Rezende Couto Nascimento, Valeria; De La Paz, Maria Fideliz; Rosandic, Jurja; Stoiber, Josef; Seyeddain, Orang; Grabner, Günther; De Toledo, Juan Alvarez; Barraquer, Rafael I.; Michael, Ralph.

In: Ophthalmic Research, Vol. 52, No. 1, 01.01.2014, p. 9-16.

Research output: Contribution to journal › Article › Research › peer-review

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AU - De Rezende Couto Nascimento, Valeria

AU - De La Paz, Maria Fideliz

AU - Rosandic, Jurja

AU - Stoiber, Josef

AU - Seyeddain, Orang

AU - Grabner, Günther

AU - De Toledo, Juan Alvarez

AU - Barraquer, Rafael I.

AU - Michael, Ralph

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N2 - Purpose: To analyse how primary diagnosis and complications affect the evolution of post-operative visual acuity (VA). Methods: We performed retrospective chart analysis on 59 eyes in 57 patients with various diagnoses, most of which were non-standard indications for Boston type 1 keratoprosthesis (Kpro) implantation. The follow-up period was at least 3 months. Patients were classified based on the evolution of post-operative VA: group A demonstrated stable VA improvement, group B lost VA improvement and group C no significant VA improvement. Results: We assigned 46% of our cases to group A with stable VA improvement, 32% to group B with lost VA improvement, and 22% to group C with no VA improvement. The number of graft failures before Kpro implantation did not influence VA outcome. Except for the relatively good VA outcome in chemical burn and radiation injury patients, there seems to be no association between primary diagnosis and positive or negative VA outcome. Only 9% of patients with posterior segment complications and 20% with infections and associated pathologies were assigned to group A. Conclusion: Most cases (78%) showed improvement in VA after Boston type 1 Kpro (groups A and B). Posterior segment complications and infections mostly resulted in persistent loss of vision. These complications should be prevented and carefully treated. © 2014 S. Karger AG, Basel.

AB - Purpose: To analyse how primary diagnosis and complications affect the evolution of post-operative visual acuity (VA). Methods: We performed retrospective chart analysis on 59 eyes in 57 patients with various diagnoses, most of which were non-standard indications for Boston type 1 keratoprosthesis (Kpro) implantation. The follow-up period was at least 3 months. Patients were classified based on the evolution of post-operative VA: group A demonstrated stable VA improvement, group B lost VA improvement and group C no significant VA improvement. Results: We assigned 46% of our cases to group A with stable VA improvement, 32% to group B with lost VA improvement, and 22% to group C with no VA improvement. The number of graft failures before Kpro implantation did not influence VA outcome. Except for the relatively good VA outcome in chemical burn and radiation injury patients, there seems to be no association between primary diagnosis and positive or negative VA outcome. Only 9% of patients with posterior segment complications and 20% with infections and associated pathologies were assigned to group A. Conclusion: Most cases (78%) showed improvement in VA after Boston type 1 Kpro (groups A and B). Posterior segment complications and infections mostly resulted in persistent loss of vision. These complications should be prevented and carefully treated. © 2014 S. Karger AG, Basel.

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