Indication for weak mutagenicity of the organophosphorus insecticide dimethoate in Drosophila melanogaster

A. Velázquez; N. Xamena; A. Creus; R. Marcos

doi:https://doi.org/10.1016/0165-1218(86)90061-3

Indication for weak mutagenicity of the organophosphorus insecticide dimethoate in Drosophila melanogaster

A. Velázquez, N. Xamena, A. Creus, R. Marcos

Department of Genetics and Microbiology

Research output: Contribution to journal › Article › Research › peer-review

16 Citations (Scopus)

Abstract

The organophosphorus insecticide dimethoate was tested for induction of genetic damage in male germ cells of Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and non-disjunction induction were studied following different routes of administration: adult feeding, injection and larval feeding. Our results show that, after injection, dimethoate induces a slight but significant increase in the frequency of point mutations. © 1986.

Original language	English
Pages (from-to)	237-243
Journal	Mutation Research/Genetic Toxicology
Volume	172
DOIs	https://doi.org/10.1016/0165-1218(86)90061-3
Publication status	Published - 1 Jan 1986

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title = "Indication for weak mutagenicity of the organophosphorus insecticide dimethoate in Drosophila melanogaster",

abstract = "The organophosphorus insecticide dimethoate was tested for induction of genetic damage in male germ cells of Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and non-disjunction induction were studied following different routes of administration: adult feeding, injection and larval feeding. Our results show that, after injection, dimethoate induces a slight but significant increase in the frequency of point mutations. {\textcopyright} 1986.",

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AU - Marcos, R.

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AB - The organophosphorus insecticide dimethoate was tested for induction of genetic damage in male germ cells of Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and non-disjunction induction were studied following different routes of administration: adult feeding, injection and larval feeding. Our results show that, after injection, dimethoate induces a slight but significant increase in the frequency of point mutations. © 1986.

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