We compare conventional cytogenetics (CC) with fluorescence in situ hybridization (FISH) in 53 untreated patients with essential thrombocythemia. CC revealed no abnormalities. When FISH was used, no BCR/ABL rearrangement nor trisomy 8 was found, but one trisomy 9, two del(13)(q14) and five del(20)(q12) were observed. FISH detected chromosome abnormalities in 15% of patients in which no alteration was found by CC.
|Publication status||Published - 1 Feb 2003|
- Conventional cytogenetics
- Essential thrombocythemia