Abstract
We compare conventional cytogenetics (CC) with fluorescence in situ hybridization (FISH) in 53 untreated patients with essential thrombocythemia. CC revealed no abnormalities. When FISH was used, no BCR/ABL rearrangement nor trisomy 8 was found, but one trisomy 9, two del(13)(q14) and five del(20)(q12) were observed. FISH detected chromosome abnormalities in 15% of patients in which no alteration was found by CC.
Original language | English |
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Pages (from-to) | 110-111 |
Journal | Haematologica |
Volume | 88 |
Issue number | 1 |
Publication status | Published - 1 Feb 2003 |
Keywords
- Conventional cytogenetics
- Essential thrombocythemia
- FISH