Incidence of trisomy 8 and 9, deletion of D13s319 and 020S108 loci and BCR/ABL translocation in non-treated essential thrombocythemia patients: An analysis of bone marrow cells using interphase fluorescence in situ hybridization

Lurdes Zamora, Blanca Espinet, Lourdes Florensa, Carles Besses, Marta Salido, Francesc Sole

Research output: Contribution to journal › Article › Research › peer-review

10 Citations (Scopus)

Abstract

We compare conventional cytogenetics (CC) with fluorescence in situ hybridization (FISH) in 53 untreated patients with essential thrombocythemia. CC revealed no abnormalities. When FISH was used, no BCR/ABL rearrangement nor trisomy 8 was found, but one trisomy 9, two del(13)(q14) and five del(20)(q12) were observed. FISH detected chromosome abnormalities in 15% of patients in which no alteration was found by CC.
Original languageEnglish
Pages (from-to)110-111
JournalHaematologica
Volume88
Issue number1
Publication statusPublished - 1 Feb 2003

Keywords

  • Conventional cytogenetics
  • Essential thrombocythemia
  • FISH

Fingerprint Dive into the research topics of 'Incidence of trisomy 8 and 9, deletion of D13s319 and 020S108 loci and BCR/ABL translocation in non-treated essential thrombocythemia patients: An analysis of bone marrow cells using interphase fluorescence in situ hybridization'. Together they form a unique fingerprint.

Cite this