© 2014 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved. Purpose: This study aims to assess inappropriate prescribing (IP) to elderly patients during the month prior to hospitalization and to compare different IP criteria.Methods: An observational, prospective and multicentric study was carried out in the internal medicine services of seven Spanish hospitals. Patients aged 75 years and olderwere randomly selected after hospital admission for a year. To assess potentially inappropriate medicines (PIMs), the Beers and STOPP criteriawere used and to assess potentially prescribing omissions (PPOs), the START criteria and ACOVE-3 medicine quality indicatorswere used. An analysis to assess factors associated with IP was performed.Results: 672 patients [median age (Q1Q3) 82 (7986) years, 55.9% female] were included. Median prescribed medicines in the month prior to hospitalization were 10(Q1Q3 713). The prevalence of IP was 87.6%, and 54.3% of patients had PIMs and PPOs concurrently. A higher prevalence rate of PIMs was predicted using the STOPP criteria thanwith the Beers criteria (p < 0.001) and a higher prevalence of PPOs using the ACOVE-3 criteria than using the START criteria (p < 0.001) was observed. Polypharmacy (≥10 medicines) was the strongest predictor of IP [OR = 11.34 95% confidence interval (CI) 4.9625.94], PIMs [OR = 14.16, 95% CI 6.4431.12], Beers-listed PIMs [OR = 8.19, 95% CI 3.0122.28] and STOPP-listed PIMs [OR = 8.21, 95% CI 3.4719.44]. PIMs was the strongest predictor of PPOs [OR = 2.79, 95% CI 1.814.28].Conclusions: A high prevalence of polypharmacy and PIMs and PPOs were reported. More than half the patients had simultaneous PIMs and PPOs. The related factors to PIMs and PPOs were different.
- Inappropriate prescribing
- Older multimorbidity patients
- Potentially inappropriate medicines
- Potentially Prescribing Omissions