Abstract
The effects of sodium dichloroisocyanurate (NaDCC) and Solprogel (Laboratories Inibsa, S.A., Barcelona, Spain), a compound that contains NaDCC plus a biodegradable polymer of acrylic acid, on the activity of DNA polymerase (DNA-P) associated with hepatitis B virus in serum were evaluated. DNA-P positive and negative pools of human serum samples were used as positive and negative stock virus. Inhibition of DNA-P activity by NaDCC and the commercial product was found to be concentration-dependent. Two minutes exposure to the minimum effective concentration of NaDCC (1000 ppm available chlorine) or Solprogel 16% (960 ppm available chlorine) totally inhibited DNA-P activity.
Original language | English |
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Pages (from-to) | 305-312 |
Journal | Journal of Hospital Infection |
Volume | 36 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1 Jan 1997 |
Keywords
- DNA-polymerase
- Hepatitis B virus
- Sodium dichloroisocyanurate
- Solprogel