TY - JOUR
T1 - In vivo reversion to the wild-type β-lactam resistance phenotype mediated by a plasmid carrying ampR and qnrA1 in Enterobacter cloacae
AU - González-López, J. J.
AU - Sabaté, M.
AU - Lavilla, S.
AU - Larrosa, M. N.
AU - Bartolomé, R. M.
AU - Prats, G.
PY - 2006/9/1
Y1 - 2006/9/1
N2 - Resistance to β-lactams and quinolones in two isogenic Enterobacter cloacae isolates was studied. One was susceptible to cefoxitin and amoxicillin-clavulanate. The other one showed its natural β-lactam resistance pattern. Both isolates had a nonfunctional AmpR regulator. However, within the second one, the presence of a plasmid carrying ampR and qnrA1 allowed reversion to the wild-type β-lactam resistance phenotype and decreased susceptibility to fluoroauinolones. Copyright © 2006, American Society for Microbiology. All Rights Reserved.
AB - Resistance to β-lactams and quinolones in two isogenic Enterobacter cloacae isolates was studied. One was susceptible to cefoxitin and amoxicillin-clavulanate. The other one showed its natural β-lactam resistance pattern. Both isolates had a nonfunctional AmpR regulator. However, within the second one, the presence of a plasmid carrying ampR and qnrA1 allowed reversion to the wild-type β-lactam resistance phenotype and decreased susceptibility to fluoroauinolones. Copyright © 2006, American Society for Microbiology. All Rights Reserved.
U2 - https://doi.org/10.1128/AAC.00273-06
DO - https://doi.org/10.1128/AAC.00273-06
M3 - Article
VL - 50
SP - 3175
EP - 3178
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
ER -