In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain

Carles Majós, Carles Aguilera, Mònica Cos, Àngels Camins, Ana P. Candiota, Teresa Delgado-Goñ, Àlex Samitier, Sara Castañer, Juan J. Sánchez, David Mato, Juan J. Acebes, Carles Arús

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29 Citations (Scopus)

Abstract

The aim of this study was to assess the usefulness of proton MR spectroscopy in the diagnosis of intraventricular tumours. Fifty-two intraventricular tumours pertaining to 16 different tumour types were derived from our database. All cases had single-voxel proton MR spectroscopy performed at TE at both 30 and 136 ms at 1.5 T. The Mann-Whitney U test was used to search for the most discriminative datapoints each tumour type. Characteristic trends were found for some groups: high Glx and Ala in meningiomas (p < 0.001 and p < 0.01, respectively), high mobile lipids in metastasis (p lt;0.001), high Cho in PNET (p < 0.001), high mI + Gly in ependymoma (p < 0.001), high NAC (p <0.01) in the absence of the normal brain parenchyma pattern in colloid cysts, and high mI/Gly and Ala in central neurocytoma. Proton MR spectroscopy provides additional metabolic information that could be useful in the diagnosis of intraventricular brain tumors. © European Society of Radiology 2009.
Original languageEnglish
Pages (from-to)2049-2059
JournalEuropean Radiology
Volume19
DOIs
Publication statusPublished - 11 Mar 2009

Keywords

  • Brain neoplasms
  • Intraventricular tumours
  • Magnetic resonance spectroscopy

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