Implication of dendritic cells in rheumatic diseases: Two paradigmatic examples

Francesc E. Borràs

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    The study and characterization of dendritic cells have deserved many efforts during the past years. This was motivated essentially because of their capacity to present antigens. So dendritic cells are named the professional antigen presenting cells. This capacity makes these cells responsible to engage the immune response and, by extension, of the pathologies related to antigen presentation, i.e. some autoimmune diseases. Some of these, including rheumatoid arthritis and systemic lupus erythematosus, are subjects of interest for reumatologists. Research during the past decade has permitted the characterization, at least in part, of the role that dendritic cells play in the development of those pathologies. The generated knowledge will help to find better treatments for these diseases.
    Original languageEnglish
    Pages (from-to)149-157
    JournalSeminarios de la Fundacion Espanola de Reumatologia
    Volume4
    Issue number4
    Publication statusPublished - 1 Sep 2003

    Keywords

    • Autoimmunity
    • Dendritic cells
    • Rheumatoid arthritis
    • SLE

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