Hydroamination of alkynes with ammonia: Unforeseen role of the gold(I) catalyst

Gábor Kovács; Agustí Lledõs; Gregori Ujaque

doi:10.1002/anie.201105309

Hydroamination of alkynes with ammonia: Unforeseen role of the gold(I) catalyst

Gábor Kovács, Agustí Lledõs, Gregori Ujaque

Department of Chemistry

Research output: Contribution to journal › Article › Research › peer-review

51 Citations (Scopus)

Abstract

Putting two and two together: Two key factors were found to account for the efficiency of the gold(I)/ligand catalyst in the hydroamination of alkynes with ammonia. On one hand, the excess nucleophile, NH 3, assists in the proton transfer, and on the other an unforeseen [Au] migration allows a feasible enamine-imine tautomerization. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Original language	English
Pages (from-to)	11147-11151
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	47
DOIs	https://doi.org/10.1002/anie.201105309
Publication status	Published - 18 Nov 2011

Keywords

alkynes
computational chemistry
density functional calculations
gold
hydroamination

Access to Document

10.1002/anie.201105309

Fingerprint Dive into the research topics of 'Hydroamination of alkynes with ammonia: Unforeseen role of the gold(I) catalyst'. Together they form a unique fingerprint.

Cite this

@article{b10825519d174b5aac6768f9feae8a07,

title = "Hydroamination of alkynes with ammonia: Unforeseen role of the gold(I) catalyst",

abstract = "Putting two and two together: Two key factors were found to account for the efficiency of the gold(I)/ligand catalyst in the hydroamination of alkynes with ammonia. On one hand, the excess nucleophile, NH 3, assists in the proton transfer, and on the other an unforeseen [Au] migration allows a feasible enamine-imine tautomerization. Copyright {\textcopyright} 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",

keywords = "alkynes, computational chemistry, density functional calculations, gold, hydroamination",

author = "G{\'a}bor Kov{\'a}cs and Agust{\'i} Lled{\~o}s and Gregori Ujaque",

year = "2011",

month = nov,

day = "18",

doi = "10.1002/anie.201105309",

language = "English",

volume = "50",

pages = "11147--11151",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "47",

}

TY - JOUR

T1 - Hydroamination of alkynes with ammonia: Unforeseen role of the gold(I) catalyst

AU - Kovács, Gábor

AU - Lledõs, Agustí

AU - Ujaque, Gregori

PY - 2011/11/18

Y1 - 2011/11/18

N2 - Putting two and two together: Two key factors were found to account for the efficiency of the gold(I)/ligand catalyst in the hydroamination of alkynes with ammonia. On one hand, the excess nucleophile, NH 3, assists in the proton transfer, and on the other an unforeseen [Au] migration allows a feasible enamine-imine tautomerization. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

AB - Putting two and two together: Two key factors were found to account for the efficiency of the gold(I)/ligand catalyst in the hydroamination of alkynes with ammonia. On one hand, the excess nucleophile, NH 3, assists in the proton transfer, and on the other an unforeseen [Au] migration allows a feasible enamine-imine tautomerization. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

KW - alkynes

KW - computational chemistry

KW - density functional calculations

KW - gold

KW - hydroamination

U2 - 10.1002/anie.201105309

DO - 10.1002/anie.201105309

M3 - Article

VL - 50

SP - 11147

EP - 11151

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

SN - 1433-7851

IS - 47

ER -