Abstract
Putting two and two together: Two key factors were found to account for the efficiency of the gold(I)/ligand catalyst in the hydroamination of alkynes with ammonia. On one hand, the excess nucleophile, NH 3, assists in the proton transfer, and on the other an unforeseen [Au] migration allows a feasible enamine-imine tautomerization. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Original language | English |
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Pages (from-to) | 11147-11151 |
Journal | Angewandte Chemie - International Edition |
Volume | 50 |
Issue number | 47 |
DOIs | |
Publication status | Published - 18 Nov 2011 |
Keywords
- alkynes
- computational chemistry
- density functional calculations
- gold
- hydroamination