Human papillomavirus detection in urine samples: An alternative screening method

Francesc Alameda, Beatriz Bellosillo, Pere Fusté, Mercè Musset, Maria Luisa Mariñoso, Gemma Mancebo, Maria Teresa Lopez-Yarto, Ramon Carreras, Sergi Serrano

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Abstract

OBJECTIVES. To investigate the usefulness of human papillomavirus detection in the urine of women with poor gynecologic attention. MATERIALS AND METHODS. Fifty urine and 50 cervical samples from 50 women were analyzed. Polymerase chain reaction was performed on these 100 samples using consensus primers and a low-density microarray-based method for human papillomavirus typing. RESULTS. The concordance of the results between both sample groups was 80%. In the urine samples, the sensitivity of polymerase chain reaction for high-grade squamous intraepithelial lesion was 100%, the specificity was 80%, the positive predictive value was 91%, and the negative predictive value was 100%. CONCLUSIONS. Human papillomavirus detection in urine samples may be used as an alternative screening method for women with poor gynecologic attention. ©2007The American Society for Colposcopy and Cervical Pathology.
Original languageEnglish
Pages (from-to)5-7
JournalJournal of Lower Genital Tract Disease
Volume11
Issue number1
DOIs
Publication statusPublished - 1 Jan 2007

Keywords

  • ASCUS
  • Cervicovaginal sample
  • HPV
  • HSIL
  • Urine sample

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