© 2019 John Wiley & Sons, Ltd. Heteronuclear long-range scalar coupling constants (nJCH) are a valuable tool for solving problems in organic chemistry and are especially suited for stereochemical and configurational analyses of small molecules and natural products. This tutorial will focus on the step-by-step implementation of several 2D 1H frequency selective HSQMBC experiments for the easy and accurate measurement of either the magnitude or both the magnitude and the sign of long-range nJCH couplings. The performance of these experiments will be showcased with several scenarios in a range of different experimental conditions.
|Journal||Magnetic Resonance in Chemistry|
|Publication status||Published - 1 Jan 2019|
- long-range proton-carbon coupling constants