Histoplasmosis in an immunocompetent man manifested 45 years after infection

Josep M. Torres-Rodríguez; Gemma Segura-Roca; Joaquín Coll

doi:10.1016/j.riam.2009.03.004

Histoplasmosis in an immunocompetent man manifested 45 years after infection

Josep M. Torres-Rodríguez, Gemma Segura-Roca, Joaquín Coll

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Abstract

We report a case of a lung reactivation of a latent histoplasmosis in a 68 year-old patient without immunologic dysfunction living in Barcelona (Spain). The Histoplasma capsulatum var. capsulatum infection was probably acquired in a previous stay in Equatorial Guinea 48 years before. Diagnosis of mild chronic pulmonary histoplasmosis was performed by histopathology of lung biopsy plus antibodies detection against H. capsulatum. Treatment with oral itraconazol during three months leaded to a complete clinical cure, and antibodies disappeared after four years of follow up. © 2008 Revista Iberoamericana de Micología.

Original language	English
Pages (from-to)	244-246
Journal	Revista Iberoamericana de Micologia
Volume	26
Issue number	4
DOIs	https://doi.org/10.1016/j.riam.2009.03.004
Publication status	Published - 1 Jan 2009

Keywords

Chronic pulmonary histoplasmosis
Equatorial Guinea
Histoplasma capsulatum var. capsulatum
Immunocompetence
Latent histoplasmosis

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10.1016/j.riam.2009.03.004

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title = "Histoplasmosis in an immunocompetent man manifested 45 years after infection",

abstract = "We report a case of a lung reactivation of a latent histoplasmosis in a 68 year-old patient without immunologic dysfunction living in Barcelona (Spain). The Histoplasma capsulatum var. capsulatum infection was probably acquired in a previous stay in Equatorial Guinea 48 years before. Diagnosis of mild chronic pulmonary histoplasmosis was performed by histopathology of lung biopsy plus antibodies detection against H. capsulatum. Treatment with oral itraconazol during three months leaded to a complete clinical cure, and antibodies disappeared after four years of follow up. {\textcopyright} 2008 Revista Iberoamericana de Micolog{\'i}a.",

keywords = "Chronic pulmonary histoplasmosis, Equatorial Guinea, Histoplasma capsulatum var. capsulatum, Immunocompetence, Latent histoplasmosis",

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year = "2009",

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T1 - Histoplasmosis in an immunocompetent man manifested 45 years after infection

AU - Torres-Rodríguez, Josep M.

AU - Segura-Roca, Gemma

AU - Coll, Joaquín

PY - 2009/1/1

Y1 - 2009/1/1

N2 - We report a case of a lung reactivation of a latent histoplasmosis in a 68 year-old patient without immunologic dysfunction living in Barcelona (Spain). The Histoplasma capsulatum var. capsulatum infection was probably acquired in a previous stay in Equatorial Guinea 48 years before. Diagnosis of mild chronic pulmonary histoplasmosis was performed by histopathology of lung biopsy plus antibodies detection against H. capsulatum. Treatment with oral itraconazol during three months leaded to a complete clinical cure, and antibodies disappeared after four years of follow up. © 2008 Revista Iberoamericana de Micología.

AB - We report a case of a lung reactivation of a latent histoplasmosis in a 68 year-old patient without immunologic dysfunction living in Barcelona (Spain). The Histoplasma capsulatum var. capsulatum infection was probably acquired in a previous stay in Equatorial Guinea 48 years before. Diagnosis of mild chronic pulmonary histoplasmosis was performed by histopathology of lung biopsy plus antibodies detection against H. capsulatum. Treatment with oral itraconazol during three months leaded to a complete clinical cure, and antibodies disappeared after four years of follow up. © 2008 Revista Iberoamericana de Micología.

KW - Chronic pulmonary histoplasmosis

KW - Equatorial Guinea

KW - Histoplasma capsulatum var. capsulatum

KW - Immunocompetence

KW - Latent histoplasmosis

U2 - 10.1016/j.riam.2009.03.004

DO - 10.1016/j.riam.2009.03.004

M3 - Article

VL - 26

SP - 244

EP - 246

IS - 4

ER -

Histoplasmosis in an immunocompetent man manifested 45 years after infection

Abstract

Keywords

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