Histopathological and virological findings in emaciated pigs from Mexico: An exploratory study

Aide Alpízar, Joaquim Segalés, Simón Martínez, Atalo Martínez, Guadalupe Socci, Dionicio Córdova, Raul Fajardo

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)


© 2018, University of Veterinary and Pharmaceutical Sciences. All rights reserved. The objective of this work was to detect the presence of three main pig respiratory viral agents (porcine rubulavirus [PorPV], porcine circovirus type 2 [PCV-2], and porcine reproductive and respiratory syndrome virus [PRRSV]) in tissues of emaciated piglets from the Bajío Region (Mexico). Necropsies and histopathological studies of 37 pigs with poor body condition were performed; viruses were detected by molecular biology methods and PCV-2 was further assessed by immunohistochemistry (IHC). Histopathologically, interstitial pneumonia was observed in 25/37 (68%) of the piglets. Also, a varying degree of lymphocyte depletion in lymphoid organs was found in 14/37 (38%) animals. Through polymerase chain reaction (PCR) and/or reverse transcription polymerase chain reaction (RT-PCR), from the 37 pigs, 16 were positive for PCV-2, 18 for PRRSV and 1 for PorPV. In accordance with these results, the infection and/or co-infection with PCV-2 and PRRSV were fairly frequent findings in piglets with poor body condition in Mexico, while the infection by PorPV was apparently negligible. Wasting of post-weaning piglets is a global pig farming problem that causes great economic losses and has been associated with diverse factors: microbial agents, environmental factors, nutritional factors, and management. When the Blue Eye Disease was first reported in Mexico, it was associated with severe wasting in post-weaning piglets. This study demonstrated that this disease does not seem to play such an important role in the wasting as was previously thought.
Original languageEnglish
Pages (from-to)213-217
JournalActa Veterinaria Brno
Issue number3
Publication statusPublished - 1 Jan 2018


  • Histopathology
  • Piglets
  • Porcine circovirus type 2
  • Porcine reproductive and respiratory syndrome virus
  • Porcine rubulavirus
  • Wasting


Dive into the research topics of 'Histopathological and virological findings in emaciated pigs from Mexico: An exploratory study'. Together they form a unique fingerprint.

Cite this