Hipoplasia pulmonar: análisis de la casuística durante 20 años

Translated title of the contribution: Pulmonary hypoplasia: An analysis of cases over a 20-year period

Yanny Paola Delgado-Peña*, Alba Torrent-Vernetta, Gabriela Sacoto, Inés de Mir-Messa, Sandra Rovira-Amigo, Silvia Gartner, Antonio Moreno-Galdó, José Andrés Molino-Gahete, Felíx Castillo-Salinas

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)


Introduction Pulmonary hypoplasia is the most frequent congenital anomaly associated with perinatal mortality. Material and methods A retrospective and descriptive review was conducted on cases of patients diagnosed with pulmonary hypoplasia between 1995 and 2014 in a tertiary university hospital. An analysis was made of the prenatal imaging, clinical manifestations, post-natal diagnostic tests, treatment and management, long-term follow up, and survival data. Results A total of 60 cases were identified, all of them with prenatal imaging. Sixteen patients required foetal surgery. Congenital diaphragmatic hernia was the most frequent diagnosis. Main clinical presentation was respiratory distress with severe hypoxemia and high requirements of mechanical ventilation. Mortality rate was 47% within first 60 days of life, and 75% for the first day of life. Pneumonia and recurrent bronchitis episodes were observed during follow-up. They had a lung function obstructive pattern, and their quality of life and exercise tolerance was good. Conclusions High neonatal mortality and significant long-term morbidity associated with pulmonary hypoplasia requires an early diagnosis and a specialised multidisciplinary team management.

Translated title of the contributionPulmonary hypoplasia: An analysis of cases over a 20-year period
Original languageSpanish
Pages (from-to)70-76
Number of pages7
JournalAnales de Pediatria
Issue number2
Publication statusPublished - 1 Aug 2016


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