Highly diastereoselective monoalkylation and Michael addition of N- (diphenylmethylene)glycinesultam under solid-liquid phase-transfer catalysis conditions using potassium carbonate as base

Anna López, Roser Pleixats

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Abstract

Treatment of a sultam-derived N-(diphenylmethylene)glycinate equivalent 1 with activated (allylic and propargylic) organic bromides and with Michael acceptors under solid-liquid phase-transfer catalysis conditions, using potassium carbonate as base, affords the monoalkylated compounds with high diastereoselectivity (>97% d.e.).
Original languageEnglish
Pages (from-to)1967-1977
JournalTetrahedron: asymmetry
Volume9
Issue number11
DOIs
Publication statusPublished - 5 Jun 1998

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