High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement

M. Montero, M. Mir, E. Sulleiro, J. L. Avalos Esquivel, E. García López, D. Molina-Morant, I. López Montesinos, L. Sorlí, G. Veliz Espinosa, E. Mounteis Oliva, M. Crespo, I. Monge, J. P. Horcajada, S. Grau, J. Pascual

Research output: Contribution to journalArticleResearch

2 Citations (Scopus)

Abstract

© 2018 The Authors There is little published data on benznidazole dosing, or levels in cerebrospinal fluid. In this report, we describe the clinical course of an immunosuppressed patient with Chagas central nervous system involvement. He was treated successfully with larger benznidazole doses than are recommended, in order to reach therapeutically effective concentrations in the brain.
Original languageEnglish
Pages (from-to)103-106
Number of pages4
JournalInternational Journal of Infectious Diseases
Volume78
DOIs
Publication statusPublished - 1 Jan 2019

Keywords

  • Benznidazole dose
  • Benznidazole PK/PD
  • Chagas disease
  • Chagoma
  • Kidney transplant recipient

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