Hepatic involvement in multiple myeloma

R. Perez-Soler, R. Esteban, E. Allende

Research output: Contribution to journalArticleResearchpeer-review


A review of 128 myelomas was made in order to assess the incidence of hepatic involvement. A hepatic histological study was made in 21. The most common lesion was diffuse plasmocytic infiltration of the liver (10/21 cases) and, less frequently, meyloid metaplasia (4/21), amyloidosis (2/21), toxic hepatitis (2/21) and extrahepatic colostasis due to pancreatic infiltration (1 case). The clinical signs of hepatic involvement were more obvious in patients with a histologically documented infiltration, ranging from hepatomegalia to the presence of portal hypertension. We reached the conclusion that liver involvement in myelomas is more common than is generally thought.
Original languageEnglish
Pages (from-to)11-14
JournalAnales de Medicina Interna
Issue number2
Publication statusPublished - 1 Jan 1984


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