Abstract
Palladium nanoparticles, prepared by the hydrogenation of Pd(dba) 2 in the presence of a tris-imidazolium iodide as stabilizer, act as an efficient catalyst for Heck and copper-free Sonogashira reactions with a range of aryl iodides and bromides at 0.2 mol-% Pd loading. Moreover, we describe a convenient protocol for the fluoride-free Hiyama coupling of vinylsilanes with aryl iodides that involves the use of sodium hydroxide as promoter in a methanol/water mixture. Under the developed conditions, one-pot, double Heck and Hiyama-Heck reactions are successfully achieved. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Original language | English |
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Pages (from-to) | 3001-3008 |
Journal | European Journal of Organic Chemistry |
Volume | 2014 |
Issue number | 14 |
DOIs | |
Publication status | Published - 1 Jan 2014 |
Keywords
- Cross-coupling
- Heterogeneous catalysis
- Nanoparticles
- Palladium