Heart failure and development of type 2 diabetes mellitus

Juana Antonia Flores-Le-Roux, David Benaiges Boix, Juan Pedro-Botet

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1 Citation (Scopus)


Heart failure and diabetes are chronic conditions that frequently concur in the same patient. DM2 is a known risk factor for the development of heart failure and is related with a worse outcome. Some studies have found that heart failure is also associated with a greater incidence of diabetes. This relationship has been less studied and the mechanisms underneath this association are not fully understood. We have done a review of the literature in search for studies that evaluate the relationship between heart failure, insulin resistance and the development of type 2 diabetes, as well as the possible mechanisms leading to this situation, such as sympathetic hyperactivation, increased concentration of free fatty acids and adiponectin resistance. © 2010 Elsevier España, S.L. All rights reserved.
Original languageEnglish
Pages (from-to)579-583
JournalMedicina Clinica
Issue number13
Publication statusPublished - 12 May 2012


  • Diabetes
  • Heart failure
  • Insulin resistance


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