Healthcare quality indicators of peripheral artery disease based on systematic reviews

S. Bellmunt, M. Roqué, D. Osorio, H. Pardo, J. R. Escudero, X. Bonfill

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)


Objectives Peripheral artery disease (PAD) is a major health problem whose clinical management includes multiple options regarding risk factor control, diagnosis, and medical and surgical treatment. The aim was to generate indicators based on systematic reviews to evaluate the quality of healthcare provided in PAD. Methods Electronic searches were run for systematic reviews in The Cochrane Library (Issue 6, 2011), MEDLINE, EMBASE, and other databases (up to June 2011). Conclusive systematic reviews of high methodological quality were selected to formulate clinical recommendations. Indicators were derived from clinical recommendations with moderate to very high strength of evidence as assessed by the GRADE system. Results From 1,804 reviews initially identified, 29 conclusive and high-quality systematic reviews were selected and nine clinical recommendations were formulated with a moderate to very high strength of recommendation. Six indicators were finally generated: four on pharmacological interventions, antiplatelet agents, naftidrofuryl, cilostazol, and statins; and two lifestyle interventions, exercise and tobacco cessation. No indicators were derived for diagnostic tests or surgical techniques. Most indicators targeted patients with intermittent claudication. Conclusions These quality indicators will help clinicians to assess the appropriateness of healthcare provided in PAD. The development of evidence-based indicators in PAD is limited by the lack of methodological quality of the research in this disease, the inconclusiveness of the evidence on diagnostic and surgical techniques, and the dynamic nature of the vascular diseases field. © 2014 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)60-69
JournalEuropean Journal of Vascular and Endovascular Surgery
Issue number1
Publication statusPublished - 1 Jan 2014


  • Delivery of healthcare
  • Peripheral vascular disease
  • Quality indicators


Dive into the research topics of 'Healthcare quality indicators of peripheral artery disease based on systematic reviews'. Together they form a unique fingerprint.

Cite this