Haemophilus influenzae meningitis in adult patients: Analysis of 12 cases

Pere Domingo, Roser Pericas, Beatriz Mirelis, Joan Nolla, Guillem Prats

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Haemophilus influenzae is an unfrequent ethiologic agent of bacterial meningitis in adult patients. In the last 12 years, it was the cause in 12 out of 238 cases (5.0%) of acute bacterial meninigitis in adults. There were 5 men and 7 women with a mean age (SD) of 45.4 (16) years (range: 18-58 years). Seven patients (60%) had a communication between subarachnoid space and skin surface or mucosal cavities, and five (41.7%) had otitis or sinusitis. Most of the strains (9/12) were serotype b. Only one patient (8.3%) developed severe neurologic and extra-neurologic complications, and was the one who died. One of the survivors (9.1%) had partial deafness. H. influenzae is not a negligible cause of bacterial meningitis in adults. Moreover, its detection has been increasing in the last years. Patients with a cerebrospinal fluid leak, otitis or sinusitis are at high risk. The outcome is usually favorable if an early adequate therapy is given.
Original languageEnglish
Pages (from-to)294-297
JournalMedicina Clinica
Volume111
Issue number8
Publication statusPublished - 19 Sep 1998

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