Genotoxicity studies with four organophosphorus insecticides using the unstable white-zeste system of Drosophila melanogaster

N. Xamena; A. Velázquez; M. Batiste-Alentorn; A. Creus; R. Marcos

doi:10.1016/0165-1218(88)90096-1

Genotoxicity studies with four organophosphorus insecticides using the unstable white-zeste system of Drosophila melanogaster

N. Xamena, A. Velázquez, M. Batiste-Alentorn, A. Creus, R. Marcos

Research output: Contribution to journal › Article › Research › peer-review

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Abstract

The present study was carried out to evaluate the suitability of the unstable white-zeste system in Drosophila melanogaster by testing 4 organophosphorus insecticides for potential genotoxic activity: dimethoate, fenitrothion, malathion, and methyl parathion. In view of the high sensitivity to insecticides of the unstable zeste strain used in this assay and the negative results obtained in this work, the white-zeste system does not appear to be sufficiently accurate for the evaluation of the mutagenic potential of specifically toxic chemicals, like insecticides. © 1988.

Original language	English
Pages (from-to)	251-256
Journal	Mutation Research
Volume	204
Issue number	2
DOIs	https://doi.org/10.1016/0165-1218(88)90096-1
Publication status	Published - 1 Jan 1988

Keywords

Drosophila melanogaster white-zeste system
Mutagenicity testing
Organophosphorus insecticides

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0165-1218(88)90096-1

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title = "Genotoxicity studies with four organophosphorus insecticides using the unstable white-zeste system of Drosophila melanogaster",

abstract = "The present study was carried out to evaluate the suitability of the unstable white-zeste system in Drosophila melanogaster by testing 4 organophosphorus insecticides for potential genotoxic activity: dimethoate, fenitrothion, malathion, and methyl parathion. In view of the high sensitivity to insecticides of the unstable zeste strain used in this assay and the negative results obtained in this work, the white-zeste system does not appear to be sufficiently accurate for the evaluation of the mutagenic potential of specifically toxic chemicals, like insecticides. {\textcopyright} 1988.",

keywords = "Drosophila melanogaster white-zeste system, Mutagenicity testing, Organophosphorus insecticides",

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AU - Xamena, N.

AU - Velázquez, A.

AU - Batiste-Alentorn, M.

AU - Creus, A.

AU - Marcos, R.

PY - 1988/1/1

Y1 - 1988/1/1

N2 - The present study was carried out to evaluate the suitability of the unstable white-zeste system in Drosophila melanogaster by testing 4 organophosphorus insecticides for potential genotoxic activity: dimethoate, fenitrothion, malathion, and methyl parathion. In view of the high sensitivity to insecticides of the unstable zeste strain used in this assay and the negative results obtained in this work, the white-zeste system does not appear to be sufficiently accurate for the evaluation of the mutagenic potential of specifically toxic chemicals, like insecticides. © 1988.

AB - The present study was carried out to evaluate the suitability of the unstable white-zeste system in Drosophila melanogaster by testing 4 organophosphorus insecticides for potential genotoxic activity: dimethoate, fenitrothion, malathion, and methyl parathion. In view of the high sensitivity to insecticides of the unstable zeste strain used in this assay and the negative results obtained in this work, the white-zeste system does not appear to be sufficiently accurate for the evaluation of the mutagenic potential of specifically toxic chemicals, like insecticides. © 1988.

KW - Drosophila melanogaster white-zeste system

KW - Mutagenicity testing

KW - Organophosphorus insecticides

U2 - 10.1016/0165-1218(88)90096-1

DO - 10.1016/0165-1218(88)90096-1

M3 - Article

VL - 204

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EP - 256

IS - 2

ER -

Genotoxicity studies with four organophosphorus insecticides using the unstable white-zeste system of Drosophila melanogaster

Abstract

Keywords

UN SDGs

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