Genotoxicity studies with four organophosphorus insecticides using the unstable white-zeste system of Drosophila melanogaster

N. Xamena, A. Velázquez, M. Batiste-Alentorn, A. Creus, R. Marcos

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Abstract

The present study was carried out to evaluate the suitability of the unstable white-zeste system in Drosophila melanogaster by testing 4 organophosphorus insecticides for potential genotoxic activity: dimethoate, fenitrothion, malathion, and methyl parathion. In view of the high sensitivity to insecticides of the unstable zeste strain used in this assay and the negative results obtained in this work, the white-zeste system does not appear to be sufficiently accurate for the evaluation of the mutagenic potential of specifically toxic chemicals, like insecticides. © 1988.
Original languageEnglish
Pages (from-to)251-256
JournalMutation Research
Volume204
Issue number2
DOIs
Publication statusPublished - 1 Jan 1988

Keywords

  • Drosophila melanogaster white-zeste system
  • Mutagenicity testing
  • Organophosphorus insecticides

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