Genotoxicity of tritiated water in human lymphocytes

G. Ribas, E. Carbonell, N. Xamena, A. Creus, R. Marcos

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Abstract

The present study was carried out to evaluate the genotoxicity of tritium, administered as tritiated water, in peripheral blood human lymphocyte cultures. Sister-chromatid exchanges (SCE) and chromosome aberrations (CA) were scored as genetic endpoints. From our results we can conclude that β-radiation from low concentrations of tritium was able to induce a significant increase in the frequency of CA, although it was ineffective in increasing the frequency of SCE. © 1994.
Original languageEnglish
Pages (from-to)63-69
JournalToxicology Letters
Volume70
Issue number1
DOIs
Publication statusPublished - 1 Jan 1994

Keywords

  • Chromosome aberrations
  • Genotoxicity
  • Human lymphocyte
  • Sister-chromatid exchange
  • Tritiated water

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