Genotoxicity of commercial petrol samples in cultured human lymphocytes

Marià Pitarque; Elisabet Carbonell; Noel Xamena; Amadeu Creus; Ricardo Marcos

Genotoxicity of commercial petrol samples in cultured human lymphocytes

Marià Pitarque, Elisabet Carbonell, Noel Xamena, Amadeu Creus, Ricardo Marcos

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Different concentrations of two petrol commercial samples, leaded and unleaded, were evaluated for genotoxicity in human peripheral blood lymphocyte cultures. Sister-chromatid exchanges (SCE) and micronuclei (MN) were scored as genetic endpoints to measure the genotoxicity of the samples in cultures set up from three different healthy donors. The treatment of the cell culture was done employing different petrol concentrations (from 0.019 to 0.312 μl/ml) From our results we can conclude that both petrol samples induced a slight but concentration-dependent increase in the frequency of SCE, while no increase was detected in the MN frequency.

Original language	English
Pages (from-to)	15-21
Journal	Revista Internacional de Contaminacion Ambiental
Volume	13
Issue number	1
Publication status	Published - 1 Dec 1997

Keywords

Human lymphocyte cultures
Micronuclei
Petrol
Sister-chromatid exchanges

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Genotoxicity of commercial petrol samples in cultured human lymphocytes",

abstract = "Different concentrations of two petrol commercial samples, leaded and unleaded, were evaluated for genotoxicity in human peripheral blood lymphocyte cultures. Sister-chromatid exchanges (SCE) and micronuclei (MN) were scored as genetic endpoints to measure the genotoxicity of the samples in cultures set up from three different healthy donors. The treatment of the cell culture was done employing different petrol concentrations (from 0.019 to 0.312 μl/ml) From our results we can conclude that both petrol samples induced a slight but concentration-dependent increase in the frequency of SCE, while no increase was detected in the MN frequency.",

keywords = "Human lymphocyte cultures, Micronuclei, Petrol, Sister-chromatid exchanges",

author = "Mari{\`a} Pitarque and Elisabet Carbonell and Noel Xamena and Amadeu Creus and Ricardo Marcos",

year = "1997",

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day = "1",

language = "English",

volume = "13",

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journal = "Revista Internacional de Contaminacion Ambiental",

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TY - JOUR

T1 - Genotoxicity of commercial petrol samples in cultured human lymphocytes

AU - Pitarque, Marià

AU - Carbonell, Elisabet

AU - Xamena, Noel

AU - Creus, Amadeu

AU - Marcos, Ricardo

PY - 1997/12/1

Y1 - 1997/12/1

N2 - Different concentrations of two petrol commercial samples, leaded and unleaded, were evaluated for genotoxicity in human peripheral blood lymphocyte cultures. Sister-chromatid exchanges (SCE) and micronuclei (MN) were scored as genetic endpoints to measure the genotoxicity of the samples in cultures set up from three different healthy donors. The treatment of the cell culture was done employing different petrol concentrations (from 0.019 to 0.312 μl/ml) From our results we can conclude that both petrol samples induced a slight but concentration-dependent increase in the frequency of SCE, while no increase was detected in the MN frequency.

AB - Different concentrations of two petrol commercial samples, leaded and unleaded, were evaluated for genotoxicity in human peripheral blood lymphocyte cultures. Sister-chromatid exchanges (SCE) and micronuclei (MN) were scored as genetic endpoints to measure the genotoxicity of the samples in cultures set up from three different healthy donors. The treatment of the cell culture was done employing different petrol concentrations (from 0.019 to 0.312 μl/ml) From our results we can conclude that both petrol samples induced a slight but concentration-dependent increase in the frequency of SCE, while no increase was detected in the MN frequency.

KW - Human lymphocyte cultures

KW - Micronuclei

KW - Petrol

KW - Sister-chromatid exchanges

M3 - Article

SN - 0188-4999

VL - 13

SP - 15

EP - 21

JO - Revista Internacional de Contaminacion Ambiental

JF - Revista Internacional de Contaminacion Ambiental

IS - 1

ER -

Genotoxicity of commercial petrol samples in cultured human lymphocytes

Abstract

Keywords

UN SDGs

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