TY - JOUR
T1 - Gender and gambling disorder
T2 - Differences in compulsivity-related neurocognitive domains
AU - Mallorquí-Bagué, Núria
AU - Mestre-Bach, Gemma
AU - Lozano-Madrid, María
AU - Granero, Roser
AU - Vintró-Alcaraz, Cristina
AU - Fernández-Aranda, Fernando
AU - Gómez-Peña, Mónica
AU - Moragas, Laura
AU - Del Pino-Gutierrez, Amparo
AU - Menchón, José M.
AU - Jiménez-Murcia, Susana
N1 - Funding Information:
The authors wish to thank the CERCA Programme/Generalitat de Catalunya for institutional support. This manuscript and research were supported by grants from the Ministerio de Ciencia, Innovación y Universidades (RTI2018-101837-B-100), funded by the Delegación del Gobierno para el Plan Nacional Sobre Drogas (Grants: 2017I067 and 2019I47), Instituto de Salud Carlos III (ISCIII) (FIS PI14/00290 and PI17/01167) and co-funded by FEDER funds/European Regional Development Fund (ERDF), a way to build Europe. CIBERObn and CIBERSAM are both initiatives of ISCIII. MLM and CVA are supported by a predoctoral Grant of the Ministerio de Educación, Cultura y Deporte (FPU15/02911 and FPU16/01453). GMB is supported by a postdoctoral grant of the Fundación Ciudadanía y Valores. The funders had no role in the study design, data collection and analysis, decision to publish, or the preparation of the manuscript.
Publisher Copyright:
© 2020 Elsevier Ltd
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2021/2
Y1 - 2021/2
N2 - Background and aims: It has been suggested that compulsivity has an essential role in gambling disorder (GD), yet there is a lack of literature exploring the link between GD, compulsivity and gender. Our main aim was to explore gender differences between two of the neurocognitive domains of compulsivity (attentional set-shifting and attentional bias and disengagement) in patients with GD and compare them with healthy controls (HCs). Methods: The sample included 57 treatment-seeking adults with GD and 60 HCs recruited from the general population. Results: The pairwise comparisons showed a worse attentional set-shifting performance in women with GD than in men (total trials (p = 0.042, |d| = 0.56), perseverative responses (p = 0.001, |d| = 0.89), trails to complete the first category (p = 0.001, |d| = 0.78) and categories completed (p = 0.001, |d| = 0.98. Also, men with GD presented higher difficulties than HC men in the two assessed compulsivity domains (attentional bias and disengagement and attentional set-shifting; Stroop interference (p = 0.015, |d| = 0.11), TMT-B (p = 0.041, |d| = 1.96) and lower scores for the WCST perseverative responses (p = 0.007, |d| = 0.78), whereas the differences observed in women with GD and HCs were most significantly in attentional set-shifting. Conclusions: This study provides the first evidence of gender compulsivity differences in GD. The results are relevant for improving current treatments by targeting specific compulsivity domains that can lead to more successful treatment options.
AB - Background and aims: It has been suggested that compulsivity has an essential role in gambling disorder (GD), yet there is a lack of literature exploring the link between GD, compulsivity and gender. Our main aim was to explore gender differences between two of the neurocognitive domains of compulsivity (attentional set-shifting and attentional bias and disengagement) in patients with GD and compare them with healthy controls (HCs). Methods: The sample included 57 treatment-seeking adults with GD and 60 HCs recruited from the general population. Results: The pairwise comparisons showed a worse attentional set-shifting performance in women with GD than in men (total trials (p = 0.042, |d| = 0.56), perseverative responses (p = 0.001, |d| = 0.89), trails to complete the first category (p = 0.001, |d| = 0.78) and categories completed (p = 0.001, |d| = 0.98. Also, men with GD presented higher difficulties than HC men in the two assessed compulsivity domains (attentional bias and disengagement and attentional set-shifting; Stroop interference (p = 0.015, |d| = 0.11), TMT-B (p = 0.041, |d| = 1.96) and lower scores for the WCST perseverative responses (p = 0.007, |d| = 0.78), whereas the differences observed in women with GD and HCs were most significantly in attentional set-shifting. Conclusions: This study provides the first evidence of gender compulsivity differences in GD. The results are relevant for improving current treatments by targeting specific compulsivity domains that can lead to more successful treatment options.
KW - Attentional bias/disengagement
KW - Attentional set-shifting
KW - Compulsivity
KW - Gambling disorder
KW - Gender
KW - Neurocognition
UR - http://www.scopus.com/inward/record.url?scp=85092081277&partnerID=8YFLogxK
U2 - 10.1016/j.addbeh.2020.106683
DO - 10.1016/j.addbeh.2020.106683
M3 - Artículo
C2 - 33038679
AN - SCOPUS:85092081277
VL - 113
M1 - 106683
ER -