Gated-SPECT Myocardial Perfusion Imaging as a Complementary Technique to Magnetic Resonance Imaging in Chronic Myocardial Infarction Patients

Gemma Cuberas-Borrós, Victor Pineda, Santiago Aguadé-Bruix, Guillermo Romero-Farina, M. Nazarena Pizzi, Gustavo De León, Joan Castell-Conesa, David García-Dorado, Jaume Candell-Riera

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Abstract

Introduction and objectives The aim of this study was to compare magnetic resonance and gated-SPECT myocardial perfusion imaging in patients with chronic myocardial infarction. Methods Magnetic resonance imaging and gated-SPECT were performed in 104 patients (mean age, 61 [12] years; 87.5% male) with a previous infarction. Left ventricular volumes and ejection fraction and classic late gadolinium enhancement viability criteria (<75% transmurality) were correlated with those of SPECT (uptake >50%) in the 17 segments of the left ventricle. Motion, thickening, and ischemia on gated-SPECT were analyzed in segments showing nonviable tissue or equivocal enhancement features (50%-75% transmurality). Results A good correlation was observed between the 2 techniques for volumes, ejection fraction (P<.05), and estimated necrotic mass (P<.01). In total, 82 of 264 segments (31%) with >75% enhancement had >50% SPECT uptake. Of the 106 equivocal segments (50%-75% enhancement) on magnetic resonance imaging, 68 (64%) had >50% uptake, 41 (38.7%) had normal motion, 46 (43.4%) had normal thickening, and 17 (16%) had ischemic criteria on SPECT. Conclusions A third of nonviable segments on magnetic resonance imaging showed >50% uptake on SPECT. Gated-SPECT can be useful in the analysis of motion, thickening, and ischemic criteria in segments with questionable viability on magnetic resonance imaging. © 2013 Sociedad Española de Cardiología. Publicado por Elsevier España, S.L. Todos los derechos reservados.
Original languageEnglish
Pages (from-to)721-727
JournalRevista Espanola de Cardiologia
Volume66
Issue number9
DOIs
Publication statusPublished - 1 Sep 2013

Keywords

  • Hibernation
  • Magnetic resonance
  • Myocardial infarction
  • Scintigraphy

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    Cuberas-Borrós, G., Pineda, V., Aguadé-Bruix, S., Romero-Farina, G., Pizzi, M. N., De León, G., Castell-Conesa, J., García-Dorado, D., & Candell-Riera, J. (2013). Gated-SPECT Myocardial Perfusion Imaging as a Complementary Technique to Magnetic Resonance Imaging in Chronic Myocardial Infarction Patients. Revista Espanola de Cardiologia, 66(9), 721-727. https://doi.org/10.1016/j.recesp.2013.04.019