Gastric vascular lesions in cirrhosis: Gastropathy and antral vascular ectasia

Meritxell Casas, Xavier Calvet, Mercedes Vergara, Maria Rosa Bella, Félix Junquera, Eva Martinez-Bauer, Rafael Campo

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Abstract

© 2014 Elsevier España, S.L.U. and AEEH y AEG. Portal hypertensive gastropathy (GHP) is a complication of portal hypertension usually associated with liver cirrhosis. The pathogenesis is unclear but the presence of portal hypertension is an essential factor for its development. GHP may be asymptomatic or present as gastrointestinal bleeding or iron deficiency anemia. Endoscopic lesions vary from a mosaic pattern to diffuse red spots; the most common location is the fundus. Treatment is indicated when there is acute or chronic bleeding, as secondary prophylaxis. There is insufficient evidence to recommend primary prophylaxis in patients who have never bled. Drugs that decrease portal pressure, such as non-cardioselective beta-blockers, and/or endoscopic ablative treatments, such as argon-beam coagulation, may be used. The role of transarterial intrahepatic portosystemic shunt) or bypass surgery has been insufficiently analyzed. Antral vascular ectasia (EVA) is a rare entity in liver cirrhosis, whose pathophysiology is still unknown. Clinical presentation is similar to that of GHP and endoscopy usually shows red spots in the antrum. Biopsy is often required to differentiate EVA from GHP. There is no effective medical therapy, so endoscopic ablative therapy and, in severe cases, antrectomy are recommended.
Original languageEnglish
Pages (from-to)97-107
JournalGastroenterologia y Hepatologia
Volume38
DOIs
Publication statusPublished - 1 Jan 2015

Keywords

  • Classification
  • Gastric antral vascular ectasia
  • Gastropathy
  • Liver cirrosis
  • Pathology
  • Portal hipertension
  • Treatment

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