Fragile sites, chromosome evolution, and human neoplasia

Rosa Miró; Inmaculada Concepción Clemente; Carmen Fuster; José Egozcue

doi:10.1007/BF00284105

Fragile sites, chromosome evolution, and human neoplasia

Rosa Miró, Inmaculada Concepción Clemente, Carmen Fuster, José Egozcue

Institute of Biotechnology and Biomedicine "Vicent Villar Palasi" (IBB)

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Abstract

In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates. © 1987 Springer-Verlag.

Original language	English
Pages (from-to)	345-349
Journal	Human Genetics
Volume	75
Issue number	4
DOIs	https://doi.org/10.1007/BF00284105
Publication status	Published - 1 Apr 1987

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title = "Fragile sites, chromosome evolution, and human neoplasia",

abstract = "In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates. {\textcopyright} 1987 Springer-Verlag.",

author = "Rosa Mir{\'o} and Clemente, {Inmaculada Concepci{\'o}n} and Carmen Fuster and Jos{\'e} Egozcue",

year = "1987",

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T1 - Fragile sites, chromosome evolution, and human neoplasia

AU - Miró, Rosa

AU - Clemente, Inmaculada Concepción

AU - Fuster, Carmen

AU - Egozcue, José

PY - 1987/4/1

Y1 - 1987/4/1

N2 - In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates. © 1987 Springer-Verlag.

AB - In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates. © 1987 Springer-Verlag.

U2 - 10.1007/BF00284105

DO - 10.1007/BF00284105

M3 - Article

SN - 0340-6717

VL - 75

SP - 345

EP - 349

JO - Human Genetics

JF - Human Genetics

IS - 4

ER -

Fragile sites, chromosome evolution, and human neoplasia

Abstract

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