First experimental determination of two-bond 13C isotopic effects on 1H NMR chemical shifts

Juan Félix Espinosa; Teodor Parella

doi:10.1016/j.tetlet.2008.02.097

First experimental determination of two-bond ¹³C isotopic effects on ¹H NMR chemical shifts

Juan Félix Espinosa, Teodor Parella

Research output: Contribution to journal › Article › Research › peer-review

3 Citations (Scopus)

Abstract

For the first time, a simple NMR methodology is proposed for the accurate determination of the effect of the substitution of 12C by 13C on the chemical shifts of protons separated by two-bonds in small molecules in their natural abundance. © 2008 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	2562-2565
Journal	Tetrahedron Letters
Volume	49
Issue number	16
DOIs	https://doi.org/10.1016/j.tetlet.2008.02.097
Publication status	Published - 14 Apr 2008

Keywords

1D-TOCSY
13 C isotopic effect
13 C-satellites
1 H chemical shift

Access to Document

10.1016/j.tetlet.2008.02.097

Cite this

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title = "First experimental determination of two-bond 13C isotopic effects on 1H NMR chemical shifts",

abstract = "For the first time, a simple NMR methodology is proposed for the accurate determination of the effect of the substitution of 12C by 13C on the chemical shifts of protons separated by two-bonds in small molecules in their natural abundance. {\textcopyright} 2008 Elsevier Ltd. All rights reserved.",

keywords = "1D-TOCSY, 13 C isotopic effect, 13 C-satellites, 1 H chemical shift",

author = "Espinosa, {Juan F{\'e}lix} and Teodor Parella",

year = "2008",

month = apr,

day = "14",

doi = "10.1016/j.tetlet.2008.02.097",

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journal = "Tetrahedron Letters",

issn = "0040-4039",

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T1 - First experimental determination of two-bond 13C isotopic effects on 1H NMR chemical shifts

AU - Espinosa, Juan Félix

AU - Parella, Teodor

PY - 2008/4/14

Y1 - 2008/4/14

N2 - For the first time, a simple NMR methodology is proposed for the accurate determination of the effect of the substitution of 12C by 13C on the chemical shifts of protons separated by two-bonds in small molecules in their natural abundance. © 2008 Elsevier Ltd. All rights reserved.

AB - For the first time, a simple NMR methodology is proposed for the accurate determination of the effect of the substitution of 12C by 13C on the chemical shifts of protons separated by two-bonds in small molecules in their natural abundance. © 2008 Elsevier Ltd. All rights reserved.

KW - 1D-TOCSY

KW - 13 C isotopic effect

KW - 13 C-satellites

KW - 1 H chemical shift

U2 - 10.1016/j.tetlet.2008.02.097

DO - 10.1016/j.tetlet.2008.02.097

M3 - Article

VL - 49

SP - 2562

EP - 2565

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 16