Abstract
For the first time, a simple NMR methodology is proposed for the accurate determination of the effect of the substitution of 12C by 13C on the chemical shifts of protons separated by two-bonds in small molecules in their natural abundance. © 2008 Elsevier Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 2562-2565 |
Journal | Tetrahedron Letters |
Volume | 49 |
Issue number | 16 |
DOIs | |
Publication status | Published - 14 Apr 2008 |
Keywords
- 1D-TOCSY
- 13 C isotopic effect
- 13 C-satellites
- 1 H chemical shift