TY - JOUR
T1 - First detection of plasmid-encoded blaOXY β-Lactamase
AU - González-López, J. J.
AU - Coelho, A.
AU - Larrosa, M. N.
AU - Lavilla, S.
AU - Bartolomé, R.
AU - Prats, G.
PY - 2009/7/1
Y1 - 2009/7/1
N2 - Three Klebsiella oxytoca isolates and one Klebsiella pneumoniae isolate from three children admitted to the Hematology Unit of Hospital Vall d'Hebron (Barcelona, Spain) exhibited a susceptibility pattern suggesting OXY β-lactamase hyperproduction. All the isolates contained a 95-kb plasmid that harbored blaOXY-1, which was transferred by electrotransformation but could not be self-transferred by conjugation. A qnrS1 gene was also harbored in the blaOXY-1-carrying plasmid. This is the first report of a plasmid-encoded OXY β-lactamase. Copyright © 2009, American Society for Microbiology. All Rights Reserved.
AB - Three Klebsiella oxytoca isolates and one Klebsiella pneumoniae isolate from three children admitted to the Hematology Unit of Hospital Vall d'Hebron (Barcelona, Spain) exhibited a susceptibility pattern suggesting OXY β-lactamase hyperproduction. All the isolates contained a 95-kb plasmid that harbored blaOXY-1, which was transferred by electrotransformation but could not be self-transferred by conjugation. A qnrS1 gene was also harbored in the blaOXY-1-carrying plasmid. This is the first report of a plasmid-encoded OXY β-lactamase. Copyright © 2009, American Society for Microbiology. All Rights Reserved.
U2 - 10.1128/AAC.01473-08
DO - 10.1128/AAC.01473-08
M3 - Article
VL - 53
SP - 3143
EP - 3146
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 7
ER -