First detection of plasmid-encoded bla<inf>OXY</inf> β-Lactamase

J. J. González-López, A. Coelho, M. N. Larrosa, S. Lavilla, R. Bartolomé, G. Prats

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8 Citations (Scopus)

Abstract

Three Klebsiella oxytoca isolates and one Klebsiella pneumoniae isolate from three children admitted to the Hematology Unit of Hospital Vall d'Hebron (Barcelona, Spain) exhibited a susceptibility pattern suggesting OXY β-lactamase hyperproduction. All the isolates contained a 95-kb plasmid that harbored blaOXY-1, which was transferred by electrotransformation but could not be self-transferred by conjugation. A qnrS1 gene was also harbored in the blaOXY-1-carrying plasmid. This is the first report of a plasmid-encoded OXY β-lactamase. Copyright © 2009, American Society for Microbiology. All Rights Reserved.
Original languageEnglish
Pages (from-to)3143-3146
JournalAntimicrobial Agents and Chemotherapy
Volume53
Issue number7
DOIs
Publication statusPublished - 1 Jul 2009

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