Fetal-maternal interface: A chronicle of allogeneic coexistence

Josep Maria Pujal, Santiago Roura, Ana M. Muñoz-Marmol, Jose Luis Mate, Antoni Bayes-Genis

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

The existence of allogeneic cells within an individual has been demonstrated in multiple fields such as hematopoietic stem cell or solid organ transplantation, non-depleted blood transfusions and the most common form which is bidirectional maternal-fetal cell trafficking, whereby cells from the fetus pass through the placental barrier. In order to graphically illustrate this early natural phenomenon that initiates the journey of a child's cells within the mother's blood and other tissues, we used a new procedure in microscopy imaging generating Large Scale Panoramic Pictures (LSPP). This technique can also be extended to explore a broad diversity of experimental models. © 2012 Landes Bioscience.
Original languageEnglish
Pages (from-to)18-20
JournalChimerism
Volume3
Issue number1
DOIs
Publication statusPublished - 1 Jan 2012

Keywords

  • Fetal-maternal interface
  • FISH
  • Microchimerism
  • Placenta
  • Tolerance

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