TY - JOUR
T1 - Exercise and preexercise nutrition as treatment for McArdle disease
AU - Nogales-Gadea, Gisela
AU - Santalla, Alfredo
AU - Ballester-Lopez, Alfonsina
AU - Arenas, Joaquín
AU - Martín, Miguel Angel
AU - Godfrey, Richard
AU - Pinís, Tomàs
AU - Pintos-Morell, Guillem
AU - Coll-Cantí, Jaume
AU - Lucia, Alejandro
PY - 2016/4/1
Y1 - 2016/4/1
N2 - © 2016 by the American College of Sports Medicine. McArdle disease is due to an inborn defect in the muscle isoform of glycogen phosphorylase (or "myophosphorylase"), the enzyme that catalyzes the first step of glycogenolysis. This condition is still not fully understood, and although advances in research would help patients immeasurably, these would also enhance our understanding of exercise metabolism. It has been 10 yr since the first published report demonstrating the benefits of regular aerobic exercise for these patients. However, misconceptions remain and the value of exercise prescription for patients with McArdle disease is still overlooked. Here, we review the role of exercise in McArdle disease with the aim to better inform health-care professionals and thus better serve the interests of patients. Recommendations for regular exercise together with preexercise nutrition in children and adult patients are also provided along with examples of exercise practice and its benefits.
AB - © 2016 by the American College of Sports Medicine. McArdle disease is due to an inborn defect in the muscle isoform of glycogen phosphorylase (or "myophosphorylase"), the enzyme that catalyzes the first step of glycogenolysis. This condition is still not fully understood, and although advances in research would help patients immeasurably, these would also enhance our understanding of exercise metabolism. It has been 10 yr since the first published report demonstrating the benefits of regular aerobic exercise for these patients. However, misconceptions remain and the value of exercise prescription for patients with McArdle disease is still overlooked. Here, we review the role of exercise in McArdle disease with the aim to better inform health-care professionals and thus better serve the interests of patients. Recommendations for regular exercise together with preexercise nutrition in children and adult patients are also provided along with examples of exercise practice and its benefits.
KW - ACTIVE LIFESTYLE
KW - DIETARY RECOMMENDATIONS
KW - EXERCISE THERAPY
KW - GLYCOGENOSIS TYPE V
KW - TRAINING
U2 - 10.1249/MSS.0000000000000812
DO - 10.1249/MSS.0000000000000812
M3 - Article
VL - 48
SP - 673
EP - 679
IS - 4
ER -