TY - JOUR
T1 - Evidence of validity and reliability of the Opiate Dosage Adequacy Scale (ODAS) in a sample of heroin addicted patients in buprenorphine/naloxone maintenance treatment
AU - González-Saiz, Francisco
AU - Lozano Rojas, Oscar
AU - Trujols, Joan
AU - Alcaraz, Saul
AU - Siñol, Núria
AU - Pérez de los Cobos, José
PY - 2018/2/1
Y1 - 2018/2/1
N2 - © 2017 Elsevier B.V. Objective The Opiate Dosage Adequacy Scale (ODAS) is a clinical tool to individually measure the “adequacy” of opioid doses in patients on maintenance treatment. The aim of this paper is to provide evidence for the validity and reliability of the ODAS in a sample of patients in buprenorphine/naloxone (B/N) maintenance treatment. Method Cross-sectional study of a convenience sample of B/N-treated patients (n = 316) from four Autonomous Communities in Spain. Participants completed a battery of instruments to assess the following: buprenorphine dose adequacy; heroin dependence severity; psychological adjustment; and patient-desired adjustment of buprenorphine dose. Results Exploratory Factor Analysis identified four factors from the ODAS that together account for 85.4% of the total variance: “Heroin craving and use”; “Overmedication”; “Objective opiate withdrawal symptoms (OWS)” and ‘Subjective OWS’. Compared to patients with an “inadequate” B/N dose (ODAS), patients with “adequate” doses had less heroin use in the last week (0.01 vs. 0.40; t = −2.73; p < 0.01, 95% CI: −0.67, −0.10), less severe heroin dependence (2.20 vs. 5.26, t = −5.14, p < 0.001; 95% CI: −4.23, −1.88), less psychological distress (3.00 vs. 6.31, t = −4.37, p < 0.001; 95% CI: −4.80, −1.81), and greater satisfaction with their doses (42.1% vs. 13.6%, χ2 = 14.44, p < 0.01). Cronbach's alpha coefficient was 0.76 (0.81, 0.92, 0.94, and 0.93, respectively, for the four factor dimensions). Conclusion These findings support the validity and reliability of the ODAS as a tool to measure and assess buprenorphine dose adequacy in the context of an opioid dependency treatment program.
AB - © 2017 Elsevier B.V. Objective The Opiate Dosage Adequacy Scale (ODAS) is a clinical tool to individually measure the “adequacy” of opioid doses in patients on maintenance treatment. The aim of this paper is to provide evidence for the validity and reliability of the ODAS in a sample of patients in buprenorphine/naloxone (B/N) maintenance treatment. Method Cross-sectional study of a convenience sample of B/N-treated patients (n = 316) from four Autonomous Communities in Spain. Participants completed a battery of instruments to assess the following: buprenorphine dose adequacy; heroin dependence severity; psychological adjustment; and patient-desired adjustment of buprenorphine dose. Results Exploratory Factor Analysis identified four factors from the ODAS that together account for 85.4% of the total variance: “Heroin craving and use”; “Overmedication”; “Objective opiate withdrawal symptoms (OWS)” and ‘Subjective OWS’. Compared to patients with an “inadequate” B/N dose (ODAS), patients with “adequate” doses had less heroin use in the last week (0.01 vs. 0.40; t = −2.73; p < 0.01, 95% CI: −0.67, −0.10), less severe heroin dependence (2.20 vs. 5.26, t = −5.14, p < 0.001; 95% CI: −4.23, −1.88), less psychological distress (3.00 vs. 6.31, t = −4.37, p < 0.001; 95% CI: −4.80, −1.81), and greater satisfaction with their doses (42.1% vs. 13.6%, χ2 = 14.44, p < 0.01). Cronbach's alpha coefficient was 0.76 (0.81, 0.92, 0.94, and 0.93, respectively, for the four factor dimensions). Conclusion These findings support the validity and reliability of the ODAS as a tool to measure and assess buprenorphine dose adequacy in the context of an opioid dependency treatment program.
KW - Buprenorphine
KW - Dosing
KW - Opioid dependence
KW - Outcomes
KW - Substitution treatment
U2 - 10.1016/j.drugalcdep.2017.10.035
DO - 10.1016/j.drugalcdep.2017.10.035
M3 - Article
C2 - 29247974
VL - 183
SP - 127
EP - 133
JO - Drug and Alcohol Dependence
JF - Drug and Alcohol Dependence
SN - 0376-8716
ER -