Evidence of agar gel electrophoresis changes of lipoprotein-x after phospholipase a and deoxycholic acid

J. C. Prison, M. R. Ras, J. Rubiés-Prat, S. Masdeu, S. Schwartz

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Abstract

The effect of phospholipase A from snake venom and deoxycholic acid on lipoprotein-X (LP-X) recovered from the cathode side of a previous agar gel electrophoresis is described. Adding phospholipase A and deoxycholic acid to the removed cathodal fraction is followed by a marked migration to the anode side on a second electrophoresis procedure. This seems to confirm that phospholipase A and bile salts act on LP-X particles modifying their agar gel electrophoretic migration characteristics. © 1977 S. Karger AG, Basel.
Original languageEnglish
Pages (from-to)199-202
JournalDigestion
Volume16
Issue number1-2
DOIs
Publication statusPublished - 1 Jan 1977

Keywords

  • Cholestasis
  • Deoxycholic acid
  • Electrophoresis
  • Lipoproteins
  • Liver disease
  • Phospholipase

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