Abstract
The antiviral activities of sodium dichloroisocyanurate (NaDCC) and a commercial product (Solprogel 2%) against human immunodeficiency virus type 1 (HIV-1) were investigated using a quantitative suspension test method. Solprogel is a compound that contains NaDCC and a biodegradable polymer of acrylic acid. Viral suspensions were prepared containing 3.2 x 106 tissue culture infective dose 50 (TCID50) in culture media. Syncytium formation in the MT-2 line and HIV antigen p24 on the supernatant of the cultures were used to determine viral titre. Results indicate that satisfactory disinfection (1000-fold reduction in 5 min) can be achieved using NaDCC and Solprogel at concentrations of 100 and 120ppm available chlorine, respectively.
Original language | English |
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Pages (from-to) | 223-228 |
Journal | Journal of Hospital Infection |
Volume | 34 |
DOIs | |
Publication status | Published - 1 Jan 1996 |
Keywords
- Disinfectant granules
- HIV
- Sodium dichloroisocyanurate
- Solprogel