Evaluation of GenoFlow DR-MTB array test for detection of rifampin and isoniazid resistance in mycobacterium tuberculosis

B. Molina-Moya, G. Kazdaglis, A. Lacoma, C. Prat, A. Gómez, R. Villar-Hernández, E. García-García, L. Haba, J. Maldonado, S. Samper, J. Ruiz-Manzano, V. Ausina, J. Domínguez

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Abstract

© Copyright 2016, American Society for Microbiology. All Rights Reserved. The aim of this study was to evaluate the GenoFlow DR-MTB array test (DiagCor Bioscience, Hong Kong) on 70 cultured isolates and 50 sputum specimens. The GenoFlow array test showed good sensitivity and specificity compared to the phenotypic Bactec 460TB. This array accurately detected mutations in rpoB, katG, and inhA associated with resistance to rifampin and isoniazid.
Original languageEnglish
Pages (from-to)1160-1163
JournalJournal of Clinical Microbiology
Volume54
Issue number4
DOIs
Publication statusPublished - 1 Apr 2016

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  • Cite this

    Molina-Moya, B., Kazdaglis, G., Lacoma, A., Prat, C., Gómez, A., Villar-Hernández, R., García-García, E., Haba, L., Maldonado, J., Samper, S., Ruiz-Manzano, J., Ausina, V., & Domínguez, J. (2016). Evaluation of GenoFlow DR-MTB array test for detection of rifampin and isoniazid resistance in mycobacterium tuberculosis. Journal of Clinical Microbiology, 54(4), 1160-1163. https://doi.org/10.1128/JCM.03341-15