Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster

N. Xamena; A. Creus; R. Marcos

doi:10.1016/0027-5107(85)90025-9

Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster

N. Xamena, A. Creus, R. Marcos

Research output: Contribution to journal › Article › Research › peer-review

Abstract

The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and translocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. © 1985.

Original language	English
Pages (from-to)	189-192
Journal	Mutation Research (Print)
Volume	149
DOIs	https://doi.org/10.1016/0027-5107(85)90025-9
Publication status	Published - 1 Jan 1985

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title = "Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster",

abstract = "The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and translocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. {\textcopyright} 1985.",

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AU - Xamena, N.

AU - Creus, A.

AU - Marcos, R.

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Y1 - 1985/1/1

N2 - The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and translocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. © 1985.

AB - The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and translocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. © 1985.

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U2 - 10.1016/0027-5107(85)90025-9

DO - 10.1016/0027-5107(85)90025-9

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VL - 149

SP - 189

EP - 192

JO - Mutation Research (Print)

JF - Mutation Research (Print)

ER -

Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster

Abstract

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