Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster

N. Xamena, A. Creus, R. Marcos

Research output: Contribution to journalArticleResearchpeer-review


The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and translocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. © 1985.
Original languageEnglish
Pages (from-to)189-192
JournalMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Publication statusPublished - 1 Jan 1985


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