TY - JOUR
T1 - Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster
AU - Xamena, N.
AU - Creus, A.
AU - Marcos, R.
PY - 1985/1/1
Y1 - 1985/1/1
N2 - The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and translocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. © 1985.
AB - The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and translocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. © 1985.
U2 - https://doi.org/10.1016/0027-5107(85)90025-9
DO - https://doi.org/10.1016/0027-5107(85)90025-9
M3 - Article
VL - 149
SP - 189
EP - 192
ER -